ELF5 and FRZB

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		ELF5	FRZB
Description		E74 like ETS transcription factor 5	frizzled related protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Extracellular Region Extracellular Space Cytoplasm Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Wnt-protein Binding
	Biological Process	Ectodermal Cell Fate Commitment Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Ectoderm Development Cell Differentiation Somatic Stem Cell Population Maintenance Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Epithelial Cell Differentiation Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development	Skeletal System Development Epithelial Cell Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Wnt Signaling Pathway Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Inner Ear Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Cell Differentiation Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Canonical Wnt Signaling Pathway Negative Regulation Of Cartilage Development Somite Development Hepatocyte Differentiation Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways		Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) Heel bone mineral density ( 28869591 30598549) Neurological blood protein biomarker levels ( 31320639) Night sleep phenotypes ( 27126917) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594) Working memory ( 31598132)
Interacting Genes		11 interacting genes: ACTR2 CRBN FRZB GLRX2 NFE2 NFE2L2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	8 interacting genes: BBS10 CYSRT1 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		2001	2487
HPRD ID		05525	07282
Ensembl ID		ENSG00000135374	ENSG00000162998
Uniprot IDs		A0A087X1W9 A8K443 Q9UKW6	D9ZGF6 Q92765
PDB IDs		1WWX
Enriched GO Terms of Interacting Partners?		Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Cellular Component Organization Regulation Of Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Integrated Stress Response Signaling Nucleus Positive Regulation Of Cellular Component Organization Cell Redox Homeostasis Regulation Of Cellular Response To Stress Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Regulation Of DNA Repair Site Of DNA Damage Negative Regulation Of Hepatocyte Differentiation Positive Regulation Of Glutathione Biosynthetic Process Regulation Of D-glucose Import Arsenate Reductase (glutaredoxin) Activity Histone H3K56 Deacetylase Activity, NAD-dependent Positive Regulation Of Fat Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Stem Cell Differentiation Regulation Of Glutathione Biosynthetic Process Regulation Of D-glucose Transmembrane Transport Aflatoxin Catabolic Process Glutathione Disulfide Oxidoreductase Activity Histone H3K9 Deacetylase Activity, Hydrolytic Mechanism Chromosome, Subtelomeric Region Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein Depalmitoylase Activity Histone H3K18 Deacetylase Activity, NAD-dependent NAD-dependent Protein Demyristoylase Activity Nuclear Proteasome Complex Positive Regulation Of Cell Projection Organization Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Double-strand Break Repair Site Of Double-strand Break Cellular Response To Stress Regulation Of RNA Metabolic Process Meiotic Chromosome Movement Towards Spindle Pole Positive Regulation Of Protein Localization To Chromatin Negative Regulation Of Autophagosome Maturation Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Proteasomal Ubiquitin-independent Protein Catabolic Process	Cell Fate Commitment Involved In Formation Of Primary Germ Layer
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