ELF5 and FRZB

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ELF5	FRZB
Gene Name		E74-like factor 5 (ets domain transcription factor)	frizzled-related protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription	G-protein Coupled Receptor Activity Wnt-protein Binding Wnt-activated Receptor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Ectoderm Development Cell Proliferation Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Epithelial Cell Differentiation	Skeletal System Development Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Development Neural Crest Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Non-canonical Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Convergent Extension Involved In Organogenesis Negative Regulation Of Cartilage Development Somite Development Negative Regulation Of Hepatocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS		β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374)	Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-Protein Interactions		8 interactors: ACTR2 FRZB NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4	7 interactors: BBS10 EHF ELF5 PNO1 POLA2 RBX1 SMAD1
Entrez ID		2001	2487
HPRD ID		05525	07282
Ensembl ID		ENSG00000135374	ENSG00000162998
Uniprot IDs		A6XAE6 A8K443 Q9UKW6	D9ZGF6 Q92765
PDB IDs		1WWX
Enriched GO Terms of Interacting Partners?			Regulation Of Transcription From RNA Polymerase II Promoter Cell Proliferation Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Primary MiRNA Processing Positive Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Epithelium Development Cellular Aromatic Compound Metabolic Process Osteoblast Fate Commitment Cellular Nitrogen Compound Metabolic Process Protein Neddylation SMAD Protein Complex Assembly Cellular Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Homeostatic Process Chaperone-mediated Protein Complex Assembly Mesodermal Cell Fate Commitment Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cardiac Muscle Cell Proliferation Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Cellular Biosynthetic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Mammary Gland Epithelial Cell Differentiation Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Macromolecule Biosynthetic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Ectoderm Development Tissue Development Nonmotile Primary Cilium Assembly Mesodermal Cell Differentiation Macromolecule Biosynthetic Process Epithelial Cell Differentiation Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cell Fate Commitment Involved In Formation Of Primary Germ Layer Protein Import Into Nucleus, Translocation DNA Strand Elongation Cardiac Muscle Tissue Growth Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Photoreceptor Cell Maintenance DNA Replication Initiation
Tagcloud ?		alveolar cited1 collectively conditional cre disruption encodes except foxa1 knockout lineage luminal master mature mechanistically mecs mmtv mutated profound rb1 represses rescued runx runx1 secretory subpopulation subpopulations tf trp53	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt7a wnt9a
Tagcloud (Difference) ?		alveolar cited1 collectively conditional cre disruption encodes except foxa1 knockout lineage luminal master mature mechanistically mecs mmtv mutated profound rb1 represses rescued runx runx1 secretory subpopulation subpopulations tf trp53	abcb1b administrated brosis colla1 corroborated dkk1 dkk2 dkk3 dkk4 fi frizzled fz1 fz5 fz7 nano nephrotoxicity osteopontin sfrp tio2 wnt1 wnt10a wnt11 wnt2 wnt3 wnt4 wnt5a wnt6 wnt7a wnt9a
Tagcloud (Intersection) ?