TOM1 and RPS27

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TOM1	RPS27
Gene Name		target of myb1 (chicken)	ribosomal protein S27
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Membrane Extracellular Vesicular Exosome	Nucleus Cytosol Ribosome Cytosolic Small Ribosomal Subunit
	Molecular Function	Protein Binding Clathrin Binding	DNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Endocytosis Protein Transport Endosomal Transport	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Translation initiation complex formation Mitotic Prometaphase Separation of Sister Chromatids Peptide chain elongation Mitotic Anaphase M Phase Influenza Life Cycle Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication Eukaryotic Translation Initiation Cap-dependent Translation Initiation Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Viral mRNA Translation Influenza Infection L13a-mediated translational silencing of Ceruloplasmin expression Cell Cycle, Mitotic Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Resolution of Sister Chromatid Cohesion Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Mitotic Metaphase and Anaphase Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APP CLTC EEA1 ILVBL MYO6 NEDD4 PTBP2 RPS27 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	13 interactors: ACTN1 ACTN4 APC C2orf44 ENOPH1 ENTPD4 HMP19 MARS NACAD PPBP RTN4 SKIL TOM1
Entrez ID		10043	6232
HPRD ID		05265	04744
Ensembl ID		ENSG00000100284	ENSG00000177954
Uniprot IDs		B3KUF5 O60784	P42677
PDB IDs		1ELK 1WRD	3J3A
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Establishment Of Localization In Cell Protein Targeting To Lysosome Endocytosis Protein Localization To Lysosome Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Localization Protein Targeting To Vacuole Protein Targeting Membrane Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Establishment Of Protein Localization To Vacuole Intracellular Protein Transport Protein Polyubiquitination Synapse Organization Protein Localization To Organelle Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Endosomal Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Receptor Internalization Regulation Of Cell Cycle Phase Transition Lysosomal Transport Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Protein Localization Neuromuscular Junction Development Regulation Of Gene Expression Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cytoplasmic Transport Immune Response Positive Regulation Of Proteolysis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Synaptic Vesicle To Endosome Fusion Transmission Of Virus Development Involved In Symbiotic Interaction TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Protein Localization To Tight Junction Tight Junction Assembly Protein Localization To Cell Junction Platelet Degranulation Apical Junction Assembly Regulation Of Cellular Component Movement Cell-cell Junction Assembly Actin Crosslink Formation Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Cell Activation Actin Filament Bundle Assembly UDP Catabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Exocytosis Positive Regulation Of Cellular Component Movement Regulation Of Cell Death Methionyl-tRNA Aminoacylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Blood Coagulation Hemostasis Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Pinocytosis Protein Complex Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cell Division Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Odontogenesis Secretion By Cell Cell Cycle Arrest Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Wound Healing L-methionine Biosynthetic Process From Methylthioadenosine Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Motility Secretion Nucleoside Diphosphate Catabolic Process L-methionine Salvage Regulation Of Locomotion
Tagcloud ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened
Tagcloud (Difference) ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened
Tagcloud (Intersection) ?