RPS27 and PPBP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		RPS27	PPBP
Description		ribosomal protein S27	pro-platelet basic protein
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Presynapse Glutamatergic Synapse GABA-ergic Synapse Ribonucleoprotein Complex	Extracellular Region Extracellular Space Platelet Alpha Granule Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Metal Ion Binding	Cytokine Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Ribosomal Small Subunit Assembly Cytoplasmic Translation RRNA Processing Translation Ribosomal Small Subunit Biogenesis	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Defense Response To Bacterium Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide D-glucose Transmembrane Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic acid Copper
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Metabolite levels ( 22916037)
Interacting Genes		16 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 MRPS18C NACAD NSG2 PPBP PSME3 PTEN RTN4 SKIL TOM1 WDCP	32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		6232	5473
HPRD ID		04744	07171
Ensembl ID		ENSG00000177954	ENSG00000163736
Uniprot IDs		P42677	P02775
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8RG0 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Lumen Cell Junction Pseudopodium	Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Antimicrobial Humoral Response Granulocyte Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Granulocyte Migration Humoral Immune Response Cytokine Activity Killing Of Cells Of Another Organism Cell Migration Cytokine-mediated Signaling Pathway Mononuclear Cell Migration Cell Motility Cell Killing CXCR Chemokine Receptor Binding Inflammatory Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response Defense Response To Other Organism Immune System Process Neutrophil Chemotaxis Immune Response CCR Chemokine Receptor Binding Chemokine Receptor Binding Neutrophil Migration Response To External Biotic Stimulus Response To Other Organism Cell-cell Signaling G Protein-coupled Receptor Signaling Pathway Signaling Cell Communication T Cell Chemotaxis Dendritic Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling CXCR3 Chemokine Receptor Binding Dendritic Cell Migration Lymphocyte Chemotaxis Neutrophil Activation Negative Regulation Of Cellular Extravasation T Cell Migration Positive Regulation Of T Cell Migration Extracellular Space
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