RPS27 and NACAD

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPS27	NACAD
Gene Name		ribosomal protein S27	NAC alpha domain containing
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Ribosome Cytosolic Small Ribosomal Subunit	Nucleus Cytoplasm
	Molecular Function	DNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Protein Transport
Pathways		Translation initiation complex formation Mitotic Prometaphase Separation of Sister Chromatids Peptide chain elongation Mitotic Anaphase M Phase Influenza Life Cycle Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication Eukaryotic Translation Initiation Cap-dependent Translation Initiation Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Viral mRNA Translation Influenza Infection L13a-mediated translational silencing of Ceruloplasmin expression Cell Cycle, Mitotic Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Resolution of Sister Chromatid Cohesion Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Mitotic Metaphase and Anaphase Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTN1 ACTN4 APC C2orf44 ENOPH1 ENTPD4 HMP19 MARS NACAD PPBP RTN4 SKIL TOM1	8 interactors: CBLC HDAC6 MAP4K2 NR4A1 PTK2 RPS27 TNNT1 YAE1D1
Entrez ID		6232	23148
HPRD ID		04744
Ensembl ID		ENSG00000177954	ENSG00000136274
Uniprot IDs		P42677	O15069
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Tight Junction Assembly Protein Localization To Cell Junction Platelet Degranulation Apical Junction Assembly Regulation Of Cellular Component Movement Cell-cell Junction Assembly Actin Crosslink Formation Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Cell Activation Actin Filament Bundle Assembly UDP Catabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Exocytosis Positive Regulation Of Cellular Component Movement Regulation Of Cell Death Methionyl-tRNA Aminoacylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Blood Coagulation Hemostasis Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Pinocytosis Protein Complex Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cell Division Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Odontogenesis Secretion By Cell Cell Cycle Arrest Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Wound Healing L-methionine Biosynthetic Process From Methylthioadenosine Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Motility Secretion Nucleoside Diphosphate Catabolic Process L-methionine Salvage Regulation Of Locomotion	Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Localization Endothelial Cell Migration Regulation Of Catalytic Activity Epithelial Cell Migration Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Hsp90 Deacetylation Epithelium Migration Regulation Of Receptor Activity Response To Growth Factor Positive Regulation Of Chaperone-mediated Protein Complex Assembly Polyubiquitinated Misfolded Protein Transport Regulation Of Proteolysis Regulation Of Epithelial Cell Migration Regulation Of Protein Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Ameboidal-type Cell Migration Netrin-activated Signaling Pathway Negative Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Cellular Macromolecule Catabolic Process Protein Complex Disassembly Negative Regulation Of Protein Metabolic Process Negative Regulation Of Synapse Assembly Slow-twitch Skeletal Muscle Fiber Contraction Aggresome Assembly Tubulin Deacetylation Positive Regulation Of Oxidative Stress-induced Cell Death Peptidyl-lysine Deacetylation Signal Complex Assembly Fc Receptor Signaling Pathway Cellular Response To Misfolded Protein Regulation Of Protein Phosphorylation Cellular Localization Positive Regulation Of Receptor Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Regulation Of MAP Kinase Activity Cellular Protein Metabolic Process Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Response To Misfolded Protein Establishment Of Organelle Localization Positive Regulation Of Cellular Metabolic Process Angiogenesis Positive Regulation Of Cell Migration
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