TOM1 and SSBP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TOM1	SSBP2
Gene Name		target of myb1 (chicken)	single-stranded DNA binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding Clathrin Binding	Single-stranded DNA Binding
	Biological Process	Intracellular Protein Transport Endocytosis Protein Transport Endosomal Transport	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Anorexia nervosa ( 21079607) Glioblastoma ( 22472174)
Protein-Protein Interactions		14 interactors: APP CLTC EEA1 ILVBL MYO6 NEDD4 PTBP2 RPS27 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	6 interactors: CDK6 EWSR1 IL36RN LDB1 LDB2 TOM1
Entrez ID		10043	23635
HPRD ID		05265	09577
Ensembl ID		ENSG00000100284
Uniprot IDs		B3KUF5 O60784	P81877
PDB IDs		1ELK 1WRD
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Establishment Of Localization In Cell Protein Targeting To Lysosome Endocytosis Protein Localization To Lysosome Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Localization Protein Targeting To Vacuole Protein Targeting Membrane Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Establishment Of Protein Localization To Vacuole Intracellular Protein Transport Protein Polyubiquitination Synapse Organization Protein Localization To Organelle Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Endosomal Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Receptor Internalization Regulation Of Cell Cycle Phase Transition Lysosomal Transport Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Protein Localization Neuromuscular Junction Development Regulation Of Gene Expression Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cytoplasmic Transport Immune Response Positive Regulation Of Proteolysis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Synaptic Vesicle To Endosome Fusion Transmission Of Virus Development Involved In Symbiotic Interaction TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Epithelial Structure Maintenance Regulation Of Erythrocyte Differentiation Stem Cell Differentiation Somatic Stem Cell Maintenance Negative Regulation Of Myeloid Cell Differentiation Hair Follicle Development Hair Cycle Process Histone H3-K4 Acetylation Cell Dedifferentiation Negative Regulation Of Interferon-gamma Secretion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Hair Cycle Antifungal Humoral Response Positive Regulation Of Hemoglobin Biosynthetic Process Negative Regulation Of Cell Differentiation Stem Cell Maintenance Regulation Of Myeloid Cell Differentiation Tissue Homeostasis Regulation Of Hemoglobin Biosynthetic Process Skin Development Multicellular Organismal Homeostasis Stem Cell Development Epithelium Development Epidermis Development Negative Regulation Of Cellular Senescence Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Interleukin-17 Production Hematopoietic Stem Cell Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Negative Regulation Of Cell Aging Cerebellar Purkinje Cell Differentiation Extracellular Negative Regulation Of Signal Transduction Cerebellar Purkinje Cell Layer Morphogenesis Dentate Gyrus Development Type B Pancreatic Cell Development Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Astrocyte Development Type B Pancreatic Cell Differentiation Negative Regulation Of Receptor Activity Lateral Ventricle Development Enteroendocrine Cell Differentiation Regulation Of Cellular Senescence Tissue Development Cerebellar Cortex Formation Defense Response To Fungus Antimicrobial Humoral Response Cell Development Glandular Epithelial Cell Development
Tagcloud ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened	abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Difference) ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened	abstract aim apc area assessment biomarkers cdkn2a chile cholecystitis cohort curve dna elisa esr1 gallbladder gbc global index material methylation operator pgp9 predictive promoter quantitative receiver specificity technique useful
Tagcloud (Intersection) ?