RPS27 and C2orf44

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPS27	C2orf44
Gene Name		ribosomal protein S27	chromosome 2 open reading frame 44
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Ribosome Cytosolic Small Ribosomal Subunit
	Molecular Function	DNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Kinase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Protein Oligomerization
Pathways		Translation initiation complex formation Mitotic Prometaphase Separation of Sister Chromatids Peptide chain elongation Mitotic Anaphase M Phase Influenza Life Cycle Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication Eukaryotic Translation Initiation Cap-dependent Translation Initiation Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Viral mRNA Translation Influenza Infection L13a-mediated translational silencing of Ceruloplasmin expression Cell Cycle, Mitotic Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Resolution of Sister Chromatid Cohesion Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Mitotic Metaphase and Anaphase Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTN1 ACTN4 APC C2orf44 ENOPH1 ENTPD4 HMP19 MARS NACAD PPBP RTN4 SKIL TOM1	12 interactors: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1
Entrez ID		6232	80304
HPRD ID		04744	07972
Ensembl ID		ENSG00000177954	ENSG00000163026
Uniprot IDs		P42677	Q9H6R7
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Tight Junction Assembly Protein Localization To Cell Junction Platelet Degranulation Apical Junction Assembly Regulation Of Cellular Component Movement Cell-cell Junction Assembly Actin Crosslink Formation Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Cell Activation Actin Filament Bundle Assembly UDP Catabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Exocytosis Positive Regulation Of Cellular Component Movement Regulation Of Cell Death Methionyl-tRNA Aminoacylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Blood Coagulation Hemostasis Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Pinocytosis Protein Complex Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cell Division Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Odontogenesis Secretion By Cell Cell Cycle Arrest Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Wound Healing L-methionine Biosynthetic Process From Methylthioadenosine Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Motility Secretion Nucleoside Diphosphate Catabolic Process L-methionine Salvage Regulation Of Locomotion	Regulation Of Cell Shape Peptidyl-serine Phosphorylation Peptidyl-amino Acid Modification Regulation Of Cell Morphogenesis Phosphorylation Cellular Response To Growth Factor Stimulus Protein Autophosphorylation Regulation Of Cellular Component Organization Response To Growth Factor Endocytosis Protein Phosphorylation Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Immune System Process Wnt Signaling Pathway Vesicle-mediated Transport Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Innate Immune Response Respiratory Burst After Phagocytosis Positive Regulation Of Phospholipase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transport Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Leukocyte Migration Involved In Immune Response Signal Transduction Response To Peptide Hormone Immune Response-regulating Signaling Pathway Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Cellular Response To Organic Substance Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Signaling Innate Immune Response-activating Signal Transduction Cell Communication Mesoderm Development Activation Of Innate Immune Response Positive Regulation Of Transferase Activity Respiratory Burst Involved In Defense Response Positive Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Cellular Response To Hormone Stimulus Immune Response
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