TOM1 and ZFYVE16

Number of citations of the paper that reports this interaction (PMID 14613930)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		TOM1	ZFYVE16
Gene Name		target of myb1 (chicken)	zinc finger, FYVE domain containing 16
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Membrane Extracellular Vesicular Exosome	Cytoplasm Early Endosome Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Transporter Activity Metal Ion Binding
	Biological Process	Intracellular Protein Transport Endocytosis Protein Transport Endosomal Transport	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway
Pathways			Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APP CLTC EEA1 ILVBL MYO6 NEDD4 PTBP2 RPS27 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	5 interactors: APP EEA1 PPP1CA RNF11 TOM1
Entrez ID		10043	9765
HPRD ID		05265	10319
Ensembl ID		ENSG00000100284	ENSG00000039319
Uniprot IDs		B3KUF5 O60784	Q7Z3T8
PDB IDs		1ELK 1WRD	3T7L
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Establishment Of Localization In Cell Protein Targeting To Lysosome Endocytosis Protein Localization To Lysosome Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Localization Protein Targeting To Vacuole Protein Targeting Membrane Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Establishment Of Protein Localization To Vacuole Intracellular Protein Transport Protein Polyubiquitination Synapse Organization Protein Localization To Organelle Intracellular Receptor Signaling Pathway Regulation Of RNA Metabolic Process Endosomal Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Receptor Internalization Regulation Of Cell Cycle Phase Transition Lysosomal Transport Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Protein Localization Neuromuscular Junction Development Regulation Of Gene Expression Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cytoplasmic Transport Immune Response Positive Regulation Of Proteolysis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Synaptic Vesicle To Endosome Fusion Transmission Of Virus Development Involved In Symbiotic Interaction TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Endocytosis Synaptic Vesicle To Endosome Fusion Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Endosomal Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Glycogen Catabolic Process Response To Light Stimulus Vesicle-mediated Transport
Tagcloud ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened
Tagcloud (Difference) ?		109qmhtt 410delta 520delta 81qnmhtt autophagosome autophagosomes colocalize d474n e478g e50k htt huntingtin ibs interfered k63 mhtt myb1 myo6 neuro2a optineurin optn polyubiquitin polyubiquitinated puncta r6 tardbpnd251 ubbd ubbddelta weakened
Tagcloud (Intersection) ?