RPS27 and ENOPH1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPS27	ENOPH1
Gene Name		ribosomal protein S27	enolase-phosphatase 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Ribosome Cytosolic Small Ribosomal Subunit	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Magnesium Ion Binding Acireductone Synthase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Sulfur Amino Acid Metabolic Process Polyamine Metabolic Process Dephosphorylation L-methionine Biosynthetic Process From Methylthioadenosine Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Translation initiation complex formation Mitotic Prometaphase Separation of Sister Chromatids Peptide chain elongation Mitotic Anaphase M Phase Influenza Life Cycle Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication Eukaryotic Translation Initiation Cap-dependent Translation Initiation Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Viral mRNA Translation Influenza Infection L13a-mediated translational silencing of Ceruloplasmin expression Cell Cycle, Mitotic Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Resolution of Sister Chromatid Cohesion Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Mitotic Metaphase and Anaphase Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTN1 ACTN4 APC C2orf44 ENOPH1 ENTPD4 HMP19 MARS NACAD PPBP RTN4 SKIL TOM1	2 interactors: RAB10 RPS27
Entrez ID		6232	58478
HPRD ID		04744	17467
Ensembl ID		ENSG00000177954	ENSG00000145293
Uniprot IDs		P42677	D6RA00 Q9UHY7
PDB IDs		3J3A	1YNS 1ZS9
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Tight Junction Assembly Protein Localization To Cell Junction Platelet Degranulation Apical Junction Assembly Regulation Of Cellular Component Movement Cell-cell Junction Assembly Actin Crosslink Formation Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Cellular Component Assembly Cell Activation Actin Filament Bundle Assembly UDP Catabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Exocytosis Positive Regulation Of Cellular Component Movement Regulation Of Cell Death Methionyl-tRNA Aminoacylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Blood Coagulation Hemostasis Regulation Of Branching Morphogenesis Of A Nerve Positive Regulation Of Pinocytosis Protein Complex Assembly Regulation Of Cell Projection Organization Positive Regulation Of Cell Division Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Odontogenesis Secretion By Cell Cell Cycle Arrest Regulation Of Sodium:proton Antiporter Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Body Fluid Levels Regulation Of Cell Migration Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Wound Healing L-methionine Biosynthetic Process From Methylthioadenosine Ribonucleoside Diphosphate Catabolic Process Endoplasmic Reticulum Tubular Network Organization Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Cell Motility Secretion Nucleoside Diphosphate Catabolic Process L-methionine Salvage Regulation Of Locomotion	Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Basolateral Protein Localization Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Organelle Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Establishment Of Neuroblast Polarity Protein Localization To Membrane Protein Localization To Organelle Endoplasmic Reticulum Tubular Network Organization Polarized Epithelial Cell Differentiation Cytoplasmic Transport Cell Proliferation Membrane Organization Intracellular Protein Transport Golgi To Plasma Membrane Protein Transport Morphogenesis Of A Polarized Epithelium Asymmetric Protein Localization Somatic Stem Cell Division Golgi To Plasma Membrane Transport Cellular Protein Localization Protein Transport Stem Cell Division Endoplasmic Reticulum Organization Establishment Of Protein Localization Intracellular Transport Neuroblast Proliferation Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Protein Localization Establishment Of Protein Localization To Plasma Membrane Vesicle Docking Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Stem Cell Proliferation Viral Transcription Membrane Docking Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Neural Precursor Cell Proliferation Establishment Of Cell Polarity Protein Secretion Cellular Localization Translational Termination Nuclear-transcribed MRNA Catabolic Process Protein Localization To Plasma Membrane Regulation Of Exocytosis MRNA Catabolic Process
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