RPS27 and MRPS18C

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		RPS27	MRPS18C
Description		ribosomal protein S27	mitochondrial ribosomal protein S18C
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Presynapse Glutamatergic Synapse GABA-ergic Synapse Ribonucleoprotein Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding Metal Ion Binding	Structural Constituent Of Ribosome Small Ribosomal Subunit RRNA Binding
	Biological Process	Ribosomal Small Subunit Assembly Cytoplasmic Translation RRNA Processing Translation Ribosomal Small Subunit Biogenesis	Translation Mitochondrial Translation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		16 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 MRPS18C NACAD NSG2 PPBP PSME3 PTEN RTN4 SKIL TOM1 WDCP	2 interacting genes: LIG4 RPS27
Entrez ID		6232	51023
HPRD ID		04744	14782
Ensembl ID		ENSG00000177954	ENSG00000163319
Uniprot IDs		P42677	D6RCM2 D6RE70 Q9Y3D5
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8RG0 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Lumen Cell Junction Pseudopodium	Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Nucleotide-excision Repair, DNA Gap Filling DNA-dependent Protein Kinase-DNA Ligase 4 Complex Immunoglobulin V(D)J Recombination Nonhomologous End Joining Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Single Strand Break Repair AMP Binding Ribosomal Small Subunit Assembly Cellular Response To Lithium Ion Response To Lithium Ion V(D)J Recombination Isotype Switching Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Somatic Diversification Of Immunoglobulins Involved In Immune Response Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Condensed Chromosome Base-excision Repair Cytosolic Small Ribosomal Subunit Somatic Cell DNA Recombination T Cell Differentiation In Thymus Somatic Diversification Of Immunoglobulins Fibroblast Proliferation Response To Gamma Radiation Positive Regulation Of Fibroblast Proliferation Double-strand Break Repair Via Nonhomologous End Joining Macromolecule Biosynthetic Process B Cell Activation Involved In Immune Response Somatic Stem Cell Population Maintenance Cellular Response To Ionizing Radiation Small-subunit Processome Ribosomal Small Subunit Biogenesis Stem Cell Proliferation DNA Biosynthetic Process Regulation Of Fibroblast Proliferation Cytosolic Ribosome Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Chromosome Organization GABA-ergic Synapse Stem Cell Population Maintenance Neuron Apoptotic Process
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