SART1 and IGHE

Number of citations of the paper that reports this interaction (PubMedID 9856836)
0

Data Source:
BioGRID (pull down)

		SART1	IGHE
Description		spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP	immunoglobulin heavy constant epsilon
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Extracellular Region Extracellular Space Plasma Membrane Membrane Immunoglobulin Complex Immunoglobulin Complex, Circulating IgE Immunoglobulin Complex IgE B Cell Receptor Complex
	Molecular Function	RNA Binding Protein Binding	Antigen Binding Protein Binding Immunoglobulin Receptor Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation	Antibody-dependent Cellular Cytotoxicity Adaptive Immune Response Immune System Process B Cell Antigen Processing And Presentation Defense Response Inflammatory Response Immune Response Complement Activation, Classical Pathway Type I Hypersensitivity Antibacterial Humoral Response Macrophage Differentiation Type 2 Immune Response B Cell Proliferation B Cell Activation Macrophage Activation Mast Cell Degranulation Eosinophil Degranulation B Cell Receptor Signaling Pathway Adaptive Immune Memory Response Primary Adaptive Immune Response Fc Receptor-mediated Immune Complex Endocytosis Mononuclear Cell Differentiation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Composite immunoglobulin trait (IgA/IgG) ( 28628107)
Interacting Genes		16 interacting genes: APP CEBPA CHERP FILNC1 HSF2BP IGHE RNF10 SNW1 SRPK2 SRSF4 SUMO2 UBC UBE2I UBL5 WBP4 ZCCHC10	1 interacting genes: SART1
Entrez ID		9092	3497
HPRD ID		10440
Ensembl ID		ENSG00000175467	ENSG00000211891
Uniprot IDs		O43290
PDB IDs		4PYU 5O9Z 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		Protein Tag Activity Macromolecule Metabolic Process MRNA Processing RNA Binding RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing Regulation Of MRNA Splicing, Via Spliceosome SUMO Transferase Activity RNA Metabolic Process MRNA Metabolic Process Nucleoplasm Regulation Of MRNA Processing Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Proteolysis Protein Modification Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding IgE B Cell Receptor Complex Nuclear Speck Regulation Of RNA Splicing SUMO Conjugating Enzyme Activity MRNA Splicing, Via Spliceosome Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Protein Sumoylation Positive Regulation Of Calcium-mediated Signaling Presynapse Acetylcholine Receptor Activator Activity Macrophage Activation Antibacterial Humoral Response Lipoprotein Particle Positive Regulation Of Protein Import Response To Vitamin B2 C/EBP Complex Acute Inflammatory Response Nucleic Acid Metabolic Process Primary Adaptive Immune Response B Cell Antigen Processing And Presentation Type I Hypersensitivity Glutamatergic Synapse Nucleic Acid Binding Positive Regulation Of Neuron Apoptotic Process PTB Domain Binding	Maturation Of 5S RRNA Positive Regulation Of Cytotoxic T Cell Differentiation MRNA Cis Splicing, Via Spliceosome Spliceosomal SnRNP Assembly U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Cajal Body Catalytic Step 2 Spliceosome Spliceosomal Complex Positive Regulation Of Lymphocyte Differentiation RRNA Processing RNA Splicing, Via Transesterification Reactions Positive Regulation Of T Cell Differentiation Positive Regulation Of Leukocyte Differentiation Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Regulation Of T Cell Differentiation Regulation Of Lymphocyte Differentiation
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