STXBP2 and DDX20

Number of citations of the paper that reports this interaction (PubMedID 11748230)
0

Data Source:
HPRD (in vivo)

		STXBP2	DDX20
Description		syntaxin binding protein 2	DEAD-box helicase 20
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Apical Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Zymogen Granule Membrane Cytolytic Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Nuclear Body Transcription Repressor Complex SMN Complex Protein-containing Complex SMN-Sm Protein Complex RNA Polymerase II Transcription Repressor Complex Gemini Of Cajal Bodies
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Leukocyte Mediated Cytotoxicity Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation Regulated Exocytosis Cellular Response To Type II Interferon Presynaptic Dense Core Vesicle Exocytosis	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Oogenesis Regulation Of Steroid Biosynthetic Process
Pathways		Platelet degranulation Other interleukin signaling	snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS			Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		14 interacting genes: DDX20 FILNC1 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2	33 interacting genes: AGO2 APP CFTR CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		6813	11218
HPRD ID		03423	05859
Ensembl ID		ENSG00000076944	ENSG00000064703
Uniprot IDs		Q15833 Q53GF4	Q9H4N4 Q9UHI6
PDB IDs		4CCA	2OXC 3B7G
Enriched GO Terms of Interacting Partners?		SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SNAP Receptor Activity SMN Complex Protein-RNA Complex Assembly Gemini Of Cajal Bodies SNARE Complex Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly RNA Splicing Exocytosis Vesicle Fusion Cellular Component Assembly Organelle Membrane Fusion Protein-containing Complex Organization 7-methylguanosine Cap Hypermethylation MRNA Processing Organelle Fusion U4 SnRNP Methylosome Vesicle Organization Membrane Fusion Vesicle Docking Specific Granule SNARE Binding MRNA Metabolic Process Organelle Localization By Membrane Tethering U1 SnRNP Secretion By Cell U5 SnRNP RNA Splicing, Via Transesterification Reactions Membrane Docking Vesicle-mediated Transport In Synapse U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Secretory Granule U2-type Spliceosomal Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex U2-type Catalytic Step 2 Spliceosome Secretion Synaptic Vesicle Exocytosis RNA Processing Calcium-ion Regulated Exocytosis Histone Pre-mRNA DCP Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex U4/U6 X U5 Tri-snRNP Complex Neuron Projection	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex U4 SnRNP Methylosome Protein-containing Complex Assembly U2 SnRNP Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions U1 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex RNA Splicing U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome PICln-Sm Protein Complex U7 SnRNP MRNA Processing U4/U6 X U5 Tri-snRNP Complex MRNA Metabolic Process U2-type Precatalytic Spliceosome Cellular Component Assembly SMN Complex RNA Processing Gemini Of Cajal Bodies Nucleoplasm MRNA Splicing, Via Spliceosome RNA Methylation Precatalytic Spliceosome Catalytic Step 2 Spliceosome RNA Binding Spliceosomal Complex Macromolecule Methylation RNA Metabolic Process RNA Modification Nucleus Nuclear Body Ribonucleoprotein Complex Methylation Protein-containing Complex Spliceosomal Tri-snRNP Complex Transcription Repressor Complex Nucleic Acid Metabolic Process Rhythmic Process Cytosol Histone Deacetylase Complex
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