DSCR9 and FBXL16

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		DSCR9	FBXL16
Description		Down syndrome critical region 9	F-box and leucine rich repeat protein 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Molecular_function	Protein Binding
	Biological Process	Biological_process	SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Eye color traits ( 20463881) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)	Attention deficit hyperactivity disorder ( 29325848) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		146 interacting genes: ACTB ACTN4 ACTR3B ADAMTS8 ADGRB3 AKAP8L ALDOA APP ASB3 ASH1L ATXN10 BEX3 BFSP1 BICD2 BTBD1 CCDC6 CD74 CELSR3 CERCAM CIAO3 CLTC CLU CNKSR1 CNOT2 COPB1 COPS4 CREBZF CTSB CXXC5 DARS1 DCAF6 DDX3X DIS3L DNAJA1 DPYSL2 DST DYNC1H1 EFEMP1 EXTL3 EYA3 FAN1 FBH1 FBXL16 FBXO11 FN1 FN3K FUZ GAR1 GIT1 GNPTAB GPRASP2 GUCY1B1 HDAC6 HNRNPK HPF1 HPS4 IFT122 IMMT ITCH JAKMIP1 KALRN KDM5A KIF1A KIF3A KLHL7 LMO7 LONRF1 LRP4 MACF1 MCRS1 METTL8 MIPOL1 MORF4L1 MTMR3 MTUS2 MYCBP2 NAGK NARS1 NBEA NCBP1 NDUFA10 NDUFB7 NEUROD6 NFE2L3 NIPBL NR4A2 OLR1 P4HTM PAK1 PAK2 PBXIP1 PCCB PDCD7 PDE4DIP PICK1 PIK3R4 PLEKHB1 PLXNB3 PPP4R1 PRKAR1A PSMC1 PSMD2 QRICH1 RAP1GAP RNF10 RSBN1L SBNO1 SEC23IP SESN3 SGSM2 SMPD3 SMURF2 SNX5 SPARCL1 SPOCK2 SPRED1 SPRY2 SPTBN1 STAMBP STX1A SULF1 SYNE1 TARS1 TNKS2 TPP1 TRIM5 TRIO TRIOBP TRIP12 TSG101 TTYH1 USP33 USP47 USP8 VARS1 VPS54 VPS9D1 WDR13 WDR26 WDR47 WRAP53 XAB2 XRN2 ZNF528 ZNFX1 ZRSR2	3 interacting genes: DSCR9 HIF1A MAPK6
Entrez ID		257203	146330
HPRD ID		10925	12365
Ensembl ID		ENSG00000230366	ENSG00000127585
Uniprot IDs			Q8N461
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytoskeleton Macromolecule Metabolic Process Cytosol Protein Metabolic Process Post-translational Protein Modification Protein Modification Process Intracellular Protein Localization Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Amyloid Fibril Formation Small GTPase Binding Cytoskeleton-dependent Intracellular Transport Identical Protein Binding Regulation Of Signal Transduction Vesicle-mediated Transport Neuron Projection Morphogenesis Transport Along Microtubule Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Projection Morphogenesis Positive Regulation Of Cellular Component Organization Positive Regulation Of Microtubule Nucleation Regulation Of Cellular Component Organization Microtubule Negative Regulation Of Signal Transduction Organelle Organization Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Organelle Organization Catabolic Process Low-density Lipoprotein Particle Receptor Binding Axo-dendritic Transport Macromolecule Catabolic Process Protein Ubiquitination Regulation Of Microtubule Cytoskeleton Organization Regulation Of Signaling Microtubule-based Transport Regulation Of Supramolecular Fiber Organization Regulation Of Intracellular Signal Transduction Centrosome Nucleus Intracellular Transport Cellular Localization Axon Cytoplasm Regulation Of Cellular Response To Stress Regulation Of Cell Communication Establishment Of Protein Localization To Vacuole Platelet Alpha Granule Lumen Establishment Of Localization In Cell Regulation Of Intrinsic Apoptotic Signaling Pathway	Elastin Metabolic Process Glandular Epithelial Cell Maturation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway DNA-binding Transcription Repressor Activity Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Mesenchymal Cell Apoptotic Process Iris Morphogenesis Columnar/cuboidal Epithelial Cell Maturation Regulation Of Thymocyte Apoptotic Process Hemoglobin Biosynthetic Process Vascular Endothelial Growth Factor Production Intracellular Oxygen Homeostasis Hypoxia-inducible Factor-1alpha Signaling Pathway Negative Regulation Of Mesenchymal Cell Apoptotic Process Insulin Secretion Involved In Cellular Response To Glucose Stimulus B-1 B Cell Homeostasis Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Axonal Transport Of Mitochondrion Hemoglobin Metabolic Process Transcription Regulator Activator Activity Neural Fold Elevation Formation Intestinal Epithelial Cell Maturation Protein Kinase Binding Protein Heterodimerization Activity Positive Regulation Of Hormone Biosynthetic Process Connective Tissue Replacement Negative Regulation Of Thymocyte Apoptotic Process Retina Vasculature Development In Camera-type Eye Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Chemokine-mediated Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Septin Cytoskeleton MAP Kinase Activity Lactate Metabolic Process Mammary Gland Epithelial Cell Differentiation Response To Iron Ion Negative Regulation Of T Cell Apoptotic Process Embryonic Hemopoiesis Negative Regulation Of MiRNA Transcription Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Dopaminergic Neuron Differentiation Epithelial Cell Maturation Glandular Epithelial Cell Differentiation Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Production B Cell Homeostasis Cardiac Ventricle Morphogenesis DNA-binding Transcription Activator Activity Response To Muscle Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?