FBXL16

Description		F-box and leucine rich repeat protein 16
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 29325848) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for body mass index ( 34021172)
Novel Interacting Genes		3 novel interacting genes: DSCR9 HIF1A MAPK6
Interacting Genes		3 interacting genes: DSCR9 HIF1A MAPK6
Entrez ID		146330
HPRD ID		12365
Ensembl ID		ENSG00000127585
Uniprot IDs		Q8N461
PDB IDs
Enriched GO Terms of Interacting Partners?		Elastin Metabolic Process Glandular Epithelial Cell Maturation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway DNA-binding Transcription Repressor Activity Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Mesenchymal Cell Apoptotic Process Iris Morphogenesis Columnar/cuboidal Epithelial Cell Maturation Regulation Of Thymocyte Apoptotic Process Hemoglobin Biosynthetic Process Vascular Endothelial Growth Factor Production Intracellular Oxygen Homeostasis Hypoxia-inducible Factor-1alpha Signaling Pathway Negative Regulation Of Mesenchymal Cell Apoptotic Process Insulin Secretion Involved In Cellular Response To Glucose Stimulus B-1 B Cell Homeostasis Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Axonal Transport Of Mitochondrion Hemoglobin Metabolic Process Transcription Regulator Activator Activity Neural Fold Elevation Formation Intestinal Epithelial Cell Maturation Protein Kinase Binding Protein Heterodimerization Activity Positive Regulation Of Hormone Biosynthetic Process Connective Tissue Replacement Negative Regulation Of Thymocyte Apoptotic Process Retina Vasculature Development In Camera-type Eye Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Chemokine-mediated Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Septin Cytoskeleton MAP Kinase Activity Lactate Metabolic Process Mammary Gland Epithelial Cell Differentiation Response To Iron Ion Negative Regulation Of T Cell Apoptotic Process Embryonic Hemopoiesis Negative Regulation Of MiRNA Transcription Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Dopaminergic Neuron Differentiation Epithelial Cell Maturation Glandular Epithelial Cell Differentiation Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Production B Cell Homeostasis Cardiac Ventricle Morphogenesis DNA-binding Transcription Activator Activity Response To Muscle Activity
Tagcloud ?