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AHCYL1 and SLC23A1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
AHCYL1
SLC23A1
Gene Name
adenosylhomocysteinase-like 1
solute carrier family 23 (ascorbic acid transporter), member 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Cytosol
Extracellular Vesicular Exosome
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Membrane
Apical Plasma Membrane
Intracellular Organelle
Extracellular Vesicular Exosome
Molecular Function
Adenosylhomocysteinase Activity
Protein Binding
Protein Binding
L-ascorbate:sodium Symporter Activity
Sodium Ion Transmembrane Transporter Activity
Nucleobase Transmembrane Transporter Activity
L-ascorbic Acid Transporter Activity
Dehydroascorbic Acid Transporter Activity
Sodium-dependent L-ascorbate Transmembrane Transporter Activity
Biological Process
MRNA Polyadenylation
Protein Export From Nucleus
One-carbon Metabolic Process
Biological_process
Positive Regulation Of Sodium Ion Transport
Regulation Of MRNA 3'-end Processing
Regulation Of Ion Transmembrane Transporter Activity
S-adenosylmethionine Cycle
Regulation Of Anion Transport
Nucleobase-containing Compound Metabolic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Sodium Ion Transport
Brain Development
Response To Toxic Substance
Nucleobase Transport
L-ascorbic Acid Transport
L-ascorbic Acid Metabolic Process
Lung Development
Vitamin Transmembrane Transport
Sodium Ion Transmembrane Transport
Small Molecule Metabolic Process
Dehydroascorbic Acid Transport
Transepithelial L-ascorbic Acid Transport
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Vitamin C (ascorbate) metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Vitamin C
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
BID
CDKN2C
DACH1
GEM
HGS
ITPR1
MEOX2
PPL
PSMD9
SLC23A1
SOX30
SRPK1
SRPK2
ZNF165
12 interactors:
ADAMTSL4
AHCYL1
KRT31
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-2
MTUS2
NOTCH2NL
Entrez ID
10768
9963
HPRD ID
07613
04810
Ensembl ID
ENSG00000168710
ENSG00000170482
Uniprot IDs
O43865
Q9UHI7
PDB IDs
3MTG
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Regulation Of Metabolic Process
Intracellular Signal Transduction
Nuclear Speck Organization
Transepithelial L-ascorbic Acid Transport
Neuron Death
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Viral Genome Replication
Positive Regulation Of Viral Process
Negative Regulation Of Viral Process
Developmental Process
Regulation Of Cell Proliferation
L-ascorbic Acid Transport
Molecular Hydrogen Transport
Regulation Of MRNA Processing
Signal Transduction In Response To DNA Damage
Regulation Of RNA Splicing
Regulation Of Cell Cycle
Gene Expression
RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Proteasome Regulatory Particle Assembly
Multicellular Organismal Development
Nucleus Organization
Voluntary Musculoskeletal Movement
Dehydroascorbic Acid Transport
Regulation Of Cellular Localization
Cell Death
Death
Regulation Of Gene Expression
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Cell Proliferation Involved In Contact Inhibition
Cellular Nitrogen Compound Metabolic Process
Nucleobase Transport
Somite Specification
Regulation Of Viral Process
G1/S Transition Of Mitotic Cell Cycle
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Glial Cell Apoptotic Process
Negative Regulation Of Calcium-mediated Signaling
Intrinsic Apoptotic Signaling Pathway
Immune Response
Cellular Macromolecular Complex Assembly
Negative Regulation Of Transcription By Competitive Promoter Binding
Sperm Chromatin Condensation
Positive Regulation Of Protein Homooligomerization
Regulation Of Secretion
Immune System Process
Tagcloud
?
abnormality
accession
attempt
csf1
elicit
exon
exons
fused
fusion
giant
karyotypic
kb
nos
nt
p11
pathogenetic
q21
replaced
replacement
s100a10
sole
stop
tag
tenosynovial
theme
transcript
tsgct
untranslated
utr
Tagcloud (Difference)
?
abnormality
accession
attempt
csf1
elicit
exon
exons
fused
fusion
giant
karyotypic
kb
nos
nt
p11
pathogenetic
q21
replaced
replacement
s100a10
sole
stop
tag
tenosynovial
theme
transcript
tsgct
untranslated
utr
Tagcloud (Intersection)
?