AHCYL1 and BID

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AHCYL1	BID
Gene Name		adenosylhomocysteinase-like 1	BH3 interacting domain death agonist
Image
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Integral Component Of Mitochondrial Membrane Extracellular Vesicular Exosome
	Molecular Function	Adenosylhomocysteinase Activity Protein Binding	Death Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Biological_process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Regulation Of Anion Transport	Release Of Cytochrome C From Mitochondria Protein Targeting To Mitochondrion Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Mitochondrial Changes Response To Estradiol Positive Regulation Of Protein Oligomerization Positive Regulation Of Protein Homooligomerization Glial Cell Apoptotic Process Regulation Of Cell Proliferation Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Protein Homooligomerization Neuron Apoptotic Process Establishment Of Protein Localization To Membrane Positive Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria Activation, translocation and oligomerization of BAX Activation, myristolyation of BID and translocation to mitochondria Programmed Cell Death Activation of BH3-only proteins Activation and oligomerization of BAK protein BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: BID CDKN2C DACH1 GEM HGS ITPR1 MEOX2 PPL PSMD9 SLC23A1 SOX30 SRPK1 SRPK2 ZNF165	36 interactors: AHCYL1 BAK1 BAX BCL2 BCL2A1 BCL2L1 BCL2L2 C14orf1 CAPN1 CAPN2 CASP1 CASP10 CASP2 CASP3 CASP8 CRMP1 CRNKL1 CSNK1A1 CSNK1E CSNK2A1 CSNK2A2 CSNK2B FBN3 GAPDH GBP2 GZMB MCL1 PLEKHM1 RBM48 REL RPA1 SETDB1 TLE1 TUBB2B YWHAB ZHX1
Entrez ID		10768	637
HPRD ID		07613	03590
Ensembl ID		ENSG00000168710	ENSG00000015475
Uniprot IDs		O43865	A8ASI8 B2ZP79 B3KT21 P55957
PDB IDs		3MTG	1ZY3 2BID 2KBW 2M5B 4BD2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Metabolic Process Intracellular Signal Transduction Nuclear Speck Organization Transepithelial L-ascorbic Acid Transport Neuron Death Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Developmental Process Regulation Of Cell Proliferation L-ascorbic Acid Transport Molecular Hydrogen Transport Regulation Of MRNA Processing Signal Transduction In Response To DNA Damage Regulation Of RNA Splicing Regulation Of Cell Cycle Gene Expression RNA Polymerase II Transcriptional Preinitiation Complex Assembly Proteasome Regulatory Particle Assembly Multicellular Organismal Development Nucleus Organization Voluntary Musculoskeletal Movement Dehydroascorbic Acid Transport Regulation Of Cellular Localization Cell Death Death Regulation Of Gene Expression Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Cellular Nitrogen Compound Metabolic Process Nucleobase Transport Somite Specification Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Glial Cell Apoptotic Process Negative Regulation Of Calcium-mediated Signaling Intrinsic Apoptotic Signaling Pathway Immune Response Cellular Macromolecular Complex Assembly Negative Regulation Of Transcription By Competitive Promoter Binding Sperm Chromatin Condensation Positive Regulation Of Protein Homooligomerization Regulation Of Secretion Immune System Process	Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrion Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Release Of Cytochrome C From Mitochondria Positive Regulation Of Cell Death Regulation Of Signal Transduction Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Potential Protein Processing Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Anoikis Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Neuron Apoptotic Process Regulation Of Anoikis Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Response To Stress Neuron Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Cell Death Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Signal Transduction Cell Communication Response To Stimulus Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Neuron Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Activation Of Cysteine-type Endopeptidase Activity Regulation Of Membrane Permeability
Tagcloud ?		abnormality accession attempt csf1 elicit exon exons fused fusion giant karyotypic kb nos nt p11 pathogenetic q21 replaced replacement s100a10 sole stop tag tenosynovial theme transcript tsgct untranslated utr	3n burns catheter caustic cd ceb ceftazidime contents corticosteroids cp created decreasing dexamethasone ensues esophageal esophagograms grouped histologic hydroxide hydroxyproline im indwelling infused massive pentoxifylline scatritial stricture tid wistar
Tagcloud (Difference) ?		abnormality accession attempt csf1 elicit exon exons fused fusion giant karyotypic kb nos nt p11 pathogenetic q21 replaced replacement s100a10 sole stop tag tenosynovial theme transcript tsgct untranslated utr	3n burns catheter caustic cd ceb ceftazidime contents corticosteroids cp created decreasing dexamethasone ensues esophageal esophagograms grouped histologic hydroxide hydroxyproline im indwelling infused massive pentoxifylline scatritial stricture tid wistar
Tagcloud (Intersection) ?