SEPT7 and CENPE

Number of citations of the paper that reports this interaction (PMID 19779646)
0

Data Source:
BioGRID (two hybrid)

		SEPT7	CENPE
Gene Name		septin 7	centromere protein E, 312kDa
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Nucleolus Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Apical Plasma Membrane Midbody Cleavage Furrow Axon Terminus Synapse Extracellular Vesicular Exosome	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Chromosome, Centromeric Region Condensed Chromosome Outer Kinetochore Nucleus Chromosome Cytoplasm Cytosol Kinesin Complex Microtubule Microtubule Cytoskeleton Membrane Midbody Mitotic Spindle Midzone
	Molecular Function	Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Kinetochore Binding
	Biological Process	Cytokinesis Mitotic Nuclear Division Regulation Of Embryonic Cell Shape Protein Heterooligomerization Cilium Morphogenesis	Mitotic Cell Cycle Microtubule-based Movement Chromosome Segregation Mitotic Chromosome Movement Towards Spindle Pole Mitotic Metaphase Plate Congression Multicellular Organismal Development Blood Coagulation Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Protein Kinase Activity Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Assembly
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Kinesins Mitotic Anaphase Factors involved in megakaryocyte development and platelet production M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion MHC class II antigen presentation Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		11 interactors: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE REL S100A4 SEPT10 SEPT11 SEPT5 SEPT9	10 interactors: BUB1B CENPF CUL1 DNAJB1 FANCA NUF2 SEPT7 SKP1 TRAF4 UBC
Entrez ID		989	1062
HPRD ID		04398	00316
Ensembl ID			ENSG00000138778
Uniprot IDs		A8K3D0 B4DNE4 Q16181	Q02224
PDB IDs		2QAG 3T5D 3TW4	1T5C
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Positive Regulation Of Cell Projection Organization Rho Protein Signal Transduction Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Septin Ring Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Ras GTPase Activity Protein Complex Assembly Septin Cytoskeleton Organization Regulation Of Cellular Component Organization Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Signaling Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Mitotic Chromosome Movement Towards Spindle Pole Glomerular Visceral Epithelial Cell Migration Regulation Of Mitotic Nuclear Division Regulation Of Ras GTPase Activity Protein Heterooligomerization Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Ras Protein Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Synaptic Vesicle Targeting Positive Regulation Of GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process Mitotic Cell Cycle Phase Transition Regulation Of Ubiquitin-protein Transferase Activity Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Mitotic Nuclear Division Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell Division Positive Regulation Of Protein Ubiquitination Notch Signaling Pathway Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Checkpoint Modification-dependent Protein Catabolic Process Circadian Rhythm SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Mitotic Spindle Checkpoint
Tagcloud ?			ags aurka aurkb bop1 bub1 bub1b ccna2 ccnb1 ccne2 cdc20 cdc25b cdc25c cdk5 cdkn1a deoxyribonucleotides earliest foxm1 illumina impdh inosine kegg mcm2 monophosphate mpa mycophenolic psrc1 rrm1 segregation transcriptomic
Tagcloud (Difference) ?			ags aurka aurkb bop1 bub1 bub1b ccna2 ccnb1 ccne2 cdc20 cdc25b cdc25c cdk5 cdkn1a deoxyribonucleotides earliest foxm1 illumina impdh inosine kegg mcm2 monophosphate mpa mycophenolic psrc1 rrm1 segregation transcriptomic
Tagcloud (Intersection) ?