SEPT7 and SEPT5

Number of citations of the paper that reports this interaction (PMID 18330356)
4

Data Source:
BioGRID (two hybrid)

		SEPT7	SEPT5
Gene Name		septin 7	septin 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Nucleolus Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Apical Plasma Membrane Midbody Cleavage Furrow Axon Terminus Synapse Extracellular Vesicular Exosome	Cytoskeleton Plasma Membrane Cell Cortex Synaptic Vesicle Terminal Bouton
	Molecular Function	Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding
	Biological Process	Cytokinesis Mitotic Nuclear Division Regulation Of Embryonic Cell Shape Protein Heterooligomerization Cilium Morphogenesis	Cytokinesis Metabolic Process Synaptic Vesicle Targeting Regulation Of Exocytosis Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS			DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		11 interactors: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE REL S100A4 SEPT10 SEPT11 SEPT5 SEPT9	18 interactors: APP KAT7 LSM8 MAGEA2B MAPK6 MYOG PARK2 PFN2 SEPT1 SEPT10 SEPT11 SEPT2 SEPT4 SEPT6 SEPT7 SEPT8 STX1A STX4
Entrez ID		989	5413
HPRD ID		04398	04100
Ensembl ID			ENSG00000184702
Uniprot IDs		A8K3D0 B4DNE4 Q16181	G3XAH0 Q99719
PDB IDs		2QAG 3T5D 3TW4
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Positive Regulation Of Cell Projection Organization Rho Protein Signal Transduction Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Septin Ring Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Ras GTPase Activity Protein Complex Assembly Septin Cytoskeleton Organization Regulation Of Cellular Component Organization Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Signaling Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Mitotic Chromosome Movement Towards Spindle Pole Glomerular Visceral Epithelial Cell Migration Regulation Of Mitotic Nuclear Division Regulation Of Ras GTPase Activity Protein Heterooligomerization Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Ras Protein Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Synaptic Vesicle Targeting Positive Regulation Of GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Cell Cycle Cell Division Regulation Of Synaptic Vesicle Transport Regulation Of Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Synaptic Transmission Positive Regulation Of Protein Ubiquitination Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Regulation Of Synaptic Vesicle Exocytosis Regulation Of Insulin Secretion Regulation Of Protein Ubiquitination Regulation Of Peptide Hormone Secretion Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Muscle Atrophy Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Secretion Positive Regulation Of Exocytosis Organelle Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Secretion Organelle Fusion Sperm Mitochondrion Organization Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Embryonic Cell Shape Positive Regulation Of Protein Metabolic Process Vesicle Docking Cellular Component Assembly Exocytosis Regulation Of Cellular Component Organization Membrane Docking Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Regulation Of Protein Localization Regulation Of Protein Secretion Cytokinesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of L-glutamate Transport Neurotransmitter Secretion
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