SEPT7 and SEPT9

Number of citations of the paper that reports this interaction (PMID 12388755)
63

Data Source:
BioGRID (affinity chromatography technology, biochemical)
HPRD (in vitro, in vivo)

		SEPT7	SEPT9
Gene Name		septin 7	septin 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Nucleolus Cytoplasm Spindle Plasma Membrane Axoneme Cell Cortex Actin Cytoskeleton Microtubule Cytoskeleton Apical Plasma Membrane Midbody Cleavage Furrow Axon Terminus Synapse Extracellular Vesicular Exosome	Stress Fiber Cytoplasm Microtubule Actin Cytoskeleton Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Cytokinesis Mitotic Nuclear Division Regulation Of Embryonic Cell Shape Protein Heterooligomerization Cilium Morphogenesis	Cell Cycle Metabolic Process Protein Heterooligomerization Cell Division
Pathways
Drugs
Diseases
GWAS			Airflow obstruction ( 22837378) Body mass index ( 20966902)
Protein-Protein Interactions		11 interactors: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE REL S100A4 SEPT10 SEPT11 SEPT5 SEPT9	10 interactors: APP HIF1A HNRNPD IKBKG NEDD4 RAB10 SEPT11 SEPT2 SEPT6 SEPT7
Entrez ID		989	10801
HPRD ID		04398	10360
Ensembl ID			ENSG00000184640
Uniprot IDs		A8K3D0 B4DNE4 Q16181	Q9UHD8
PDB IDs		2QAG 3T5D 3TW4
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Positive Regulation Of Cell Projection Organization Rho Protein Signal Transduction Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Septin Ring Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Ras GTPase Activity Protein Complex Assembly Septin Cytoskeleton Organization Regulation Of Cellular Component Organization Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Signaling Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Mitotic Chromosome Movement Towards Spindle Pole Glomerular Visceral Epithelial Cell Migration Regulation Of Mitotic Nuclear Division Regulation Of Ras GTPase Activity Protein Heterooligomerization Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Ras Protein Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Synaptic Vesicle Targeting Positive Regulation Of GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Cell Division Cell Morphogenesis Neuron Differentiation Cell Projection Organization Intracellular Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway B Cell Homeostasis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Anatomical Structure Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Axon Cargo Transport Neuromuscular Junction Development Generation Of Neurons Neuron Projection Development Regulation Of DNA-templated Transcription In Response To Stress Cell Projection Morphogenesis Cell Part Morphogenesis Visual Learning Outflow Tract Morphogenesis Neurogenesis Response To Light Stimulus Visual Behavior Lymphocyte Homeostasis Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Neural Fold Elevation Formation Transmission Of Virus Basolateral Protein Localization Development Involved In Symbiotic Interaction Neuron Development Cell Development Associative Learning Leukocyte Homeostasis Regulation Of Synapse Structure Or Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Radiation Establishment Of Localization In Cell Synaptic Growth At Neuromuscular Junction Elastin Metabolic Process Regulation Of Embryonic Cell Shape Cytokinesis Immune System Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Establishment Of Neuroblast Polarity Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Collateral Sprouting In Absence Of Injury Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Viral Process Nervous System Development
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