CD81 and CD9

Number of citations of the paper that reports this interaction (PMID 8630057)
11

Data Source:
HPRD (in vivo)

		CD81	CD9
Gene Name		CD81 molecule	CD9 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding	Integrin Binding Protein Binding
	Biological Process	Activation Of MAPK Activity Phosphatidylinositol Biosynthetic Process Protein Localization Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Phosphatidylinositol Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Regulation Of Cell Motility	Platelet Degranulation Movement Of Cell Or Subcellular Component Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Brain Development Blood Coagulation Negative Regulation Of Cell Proliferation Pathogenesis Response To Water Deprivation Oligodendrocyte Development Platelet Activation Paranodal Junction Assembly Multicellular Organism Reproduction
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Uptake and actions of bacterial toxins Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Fertilization Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs
Diseases
GWAS			Mean platelet volume ( 22139419) Paclitaxel-induced neuropathy ( 23776197) Platelet counts ( 22139419)
Protein-Protein Interactions		20 interactors: ADRB2 CD19 CD9 CSNK2B DLG5 HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT MYOC PTGFRN RBBP6 RNF128 SHC1 TSPAN4 VKORC1 ZBTB16	22 interactors: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1
Entrez ID		975	928
HPRD ID		08924	00880
Ensembl ID		ENSG00000110651	ENSG00000010278
Uniprot IDs		E9PJK1 P60033	B4DK09 P21926
PDB IDs		1G8Q 1IV5 2AVZ
Enriched GO Terms of Interacting Partners?		Organ Development ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation System Development Regulation Of Immune Response Regulation Of Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Developmental Process Positive Regulation Of Ossification B Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Response To Stress Negative Regulation Of Cell Proliferation Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement B Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Tissue Development Fibroblast Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Signal Transduction Innate Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Ossification Stem Cell Division Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Single Organismal Cell-cell Adhesion Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Differentiation Bone Development Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of FasL Biosynthetic Process Zonula Adherens Assembly ERBB2-ERBB3 Signaling Pathway Mast Cell Proliferation Lymphocyte Differentiation	Wound Healing Blood Coagulation Hemostasis Response To Wounding Regulation Of Body Fluid Levels Response To Stress Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Adhesion Integrin-mediated Signaling Pathway Regulation Of Immune System Process Regulation Of Protein Metabolic Process Learning Or Memory Cognition Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Proliferation Cell Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Regulation Of Cell Migration Extracellular Matrix Organization Associative Learning Extracellular Structure Organization Locomotion Cell Motility Positive Regulation Of Signal Transduction Regulation Of Cell Adhesion Positive Regulation Of Epithelial Cell Migration Regulation Of Cellular Amino Acid Metabolic Process Tissue Development Cell-substrate Adhesion Positive Regulation Of Endocytosis Leukocyte Migration Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Single-organism Behavior Mesodermal Cell Differentiation Movement Of Cell Or Subcellular Component Positive Regulation Of Cell-substrate Adhesion Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling
Tagcloud ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle	accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Difference) ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle	accessibility agvhd allergy allobmt analogous buffy cationic cd23 cd25 clarified coat destructive dr eg2 eosinophil eosinophilia eosinophilic eosinophils epitope fog formaldehyde intravenously methylprednisolone myristate octylglucopyranoside pbes recognizing rhil transplanted
Tagcloud (Intersection) ?