CD81 and PTGFRN

Number of citations of the paper that reports this interaction (PMID 11278880)
49

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		CD81	PTGFRN
Gene Name		CD81 molecule	prostaglandin F2 receptor inhibitor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding	Protein Binding
	Biological Process	Activation Of MAPK Activity Phosphatidylinositol Biosynthetic Process Protein Localization Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Phosphatidylinositol Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Regulation Of Cell Motility	Lipid Particle Organization
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Erectile dysfunction and prostate cancer treatment ( 20932654)
Protein-Protein Interactions		20 interactors: ADRB2 CD19 CD9 CSNK2B DLG5 HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT MYOC PTGFRN RBBP6 RNF128 SHC1 TSPAN4 VKORC1 ZBTB16	5 interactors: CD151 CD63 CD81 CD82 CD9
Entrez ID		975	5738
HPRD ID		08924	03124
Ensembl ID		ENSG00000110651	ENSG00000134247
Uniprot IDs		E9PJK1 P60033	Q9P2B2
PDB IDs		1G8Q 1IV5 2AVZ
Enriched GO Terms of Interacting Partners?		Organ Development ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation System Development Regulation Of Immune Response Regulation Of Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Developmental Process Positive Regulation Of Ossification B Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Response To Stress Negative Regulation Of Cell Proliferation Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement B Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Tissue Development Fibroblast Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Signal Transduction Innate Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Ossification Stem Cell Division Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Single Organismal Cell-cell Adhesion Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Differentiation Bone Development Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of FasL Biosynthetic Process Zonula Adherens Assembly ERBB2-ERBB3 Signaling Pathway Mast Cell Proliferation Lymphocyte Differentiation	Platelet Degranulation Cell Activation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Platelet Activation Cell Junction Assembly Cell Adhesion Locomotion Receptor-mediated Virion Attachment To Host Cell Regulation Of Rubidium Ion Transport Response To Water Deprivation Movement Of Cell Or Subcellular Component Exocytosis Virion Attachment To Host Cell Endosome To Melanosome Transport Pigment Granule Maturation Adhesion Of Symbiont To Host Cellular Pigment Accumulation Positive Regulation Of Integrin-mediated Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Blood Coagulation Hemostasis Hemidesmosome Assembly Fusion Of Sperm To Egg Plasma Membrane Paranodal Junction Assembly Secretion By Cell Plasma Membrane Fusion Positive Regulation Of Receptor Internalization Regulation Of Body Fluid Levels Wound Healing Secretion Response To Wounding Myelin Assembly Regulation Of Receptor Internalization Cell Proliferation Regulation Of Integrin-mediated Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell Oligodendrocyte Development Cell Migration Entry Into Host Cell Cell Motility Cell-substrate Junction Assembly Regulation Of B Cell Proliferation Regulation Of Lipid Kinase Activity Cellular Pigmentation Developmental Pigmentation T Cell Proliferation Positive Regulation Of B Cell Activation Oligodendrocyte Differentiation
Tagcloud ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Difference) ?		000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Intersection) ?