CD9 and TSPAN4

Number of citations of the paper that reports this interaction (PubMedID 9360996)
0

Data Source:
HPRD (in vivo)

		CD9	TSPAN4
Description		CD9 molecule	tetraspanin 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle	Plasma Membrane Focal Adhesion Membrane Vesicle
	Molecular Function	Integrin Binding Protein Binding	Antigen Binding Integrin Binding Protein Binding
	Biological Process	Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Nervous System Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Glial Cell Migration Oligodendrocyte Development Myoblast Fusion Involved In Skeletal Muscle Regeneration Cell Differentiation Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation Regulation Of Macrophage Migration	Protein-containing Complex Assembly
Pathways		Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs		C31G
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 27863252 32888494) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 22139419 26805783)	Falling risk ( 32999390)
Interacting Genes		25 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT ODF4 PRKCA PTGFRN SERPINH1 SLC22A1 SLC22A2 TSPAN4 VKORC1	49 interacting genes: CATSPER1 CD46 CD81 CD9 CHRD CLDN11 CLEC2D CREB3 CREB5 CYSRT1 EVA1A FCHO1 FRS3 GNE GRN GUCD1 HOXA1 ITGA3 ITGA6 ITGB1 KRTAP10-1 KRTAP10-8 KRTAP4-11 KRTAP4-5 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE2B LCE2D LCE3A LCE3C LCE3D LCE4A LRRC25 LTB4R2 MDFI MGAT5B MKRN3 NBPF19 NOTCH2NLA NR4A3 OTX1 PHLDA1 PLSCR4 SGPL1 TEKT4 TMEM106A VGLL3
Entrez ID		928	7106
HPRD ID		00880	04033
Ensembl ID		ENSG00000010278	ENSG00000214063
Uniprot IDs		A0A087WU13 A6NNI4 B4DK09 G8JLH6 P21926	A8MVV6 O14817
PDB IDs		6K4J 6RLO 6RLR 6Z1V 6Z20
Enriched GO Terms of Interacting Partners?		Cell Surface Integrin Binding Membrane Plasma Membrane External Side Of Plasma Membrane System Process Integrin Complex Regulation Of Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Motility Positive Regulation Of Locomotion Learning Or Memory Regulation Of Locomotion Developmental Process Cognition Cell-matrix Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Cell Communication Protein-containing Complex Binding Regulation Of Multicellular Organismal Process Regulation Of System Process Wound Healing, Spreading Of Epidermal Cells Mesodermal Cell Differentiation Integrin Alpha3-beta1 Complex Integrin Alpha5-beta1 Complex Pyrimidine Nucleoside Transmembrane Transporter Activity Vascular Process In Circulatory System Focal Adhesion Import Into Cell Regulation Of Epithelial Cell Migration Neurotransmitter Reuptake Laminin Binding Cell Adhesion Cell-substrate Adhesion Positive Regulation Of Signaling Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Alpha2-beta1 Complex Putrescine Transmembrane Transporter Activity Virus Receptor Activity Circulatory System Process Regulation Of Biological Quality Positive Regulation Of Protein Localization To Membrane Myoblast Fusion Cell Adhesion Mediated By Integrin Positive Regulation Of Signal Transduction Receptor Complex Wound Healing, Spreading Of Cells Neurotransmitter Uptake Response To Muscle Activity	Keratinization Epidermis Development Keratin Filament Intermediate Filament Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Myoblast Fusion Involved In Skeletal Muscle Regeneration Myoblast Fusion Integrin Complex Cellular Response To Low-density Lipoprotein Particle Stimulus Cellular Response To Lipoprotein Particle Stimulus Cell-cell Fusion Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Cerebellar Climbing Fiber To Purkinje Cell Synapse Identical Protein Binding CAMP Response Element Binding Regulation Of Cell Motility Hair Cycle Regulation Of Locomotion Integrin Binding Mesodermal Cell Differentiation Tissue Development
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