CD9 and ODF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD9	ODF4
Description		CD9 molecule	outer dense fiber of sperm tails 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle	Membrane
	Molecular Function	Integrin Binding Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Nervous System Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Glial Cell Migration Oligodendrocyte Development Myoblast Fusion Involved In Skeletal Muscle Regeneration Cell Differentiation Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation Regulation Of Macrophage Migration	Spermatogenesis Cell Differentiation
Pathways		Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs		C31G
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 27863252 32888494) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 22139419 26805783)	Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		25 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT ODF4 PRKCA PTGFRN SERPINH1 SLC22A1 SLC22A2 TSPAN4 VKORC1	22 interacting genes: APP CACNG1 CD9 CDIPT CNIH3 DEFB103A DEFB103B EBP LAPTM4B MARCHF5 MEOX2 MS4A13 NINJ2 RUSF1 SACM1L SLC25A46 SLC38A7 TMEM119 TMEM239 TOMM6 TRARG1 YIPF6
Entrez ID		928	146852
HPRD ID		00880	17658
Ensembl ID		ENSG00000010278	ENSG00000184650
Uniprot IDs		A0A087WU13 A6NNI4 B4DK09 G8JLH6 P21926	C3TX97 Q2M2E3
PDB IDs		6K4J 6RLO 6RLR 6Z1V 6Z20
Enriched GO Terms of Interacting Partners?		Cell Surface Integrin Binding Membrane Plasma Membrane External Side Of Plasma Membrane System Process Integrin Complex Regulation Of Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Motility Positive Regulation Of Locomotion Learning Or Memory Regulation Of Locomotion Developmental Process Cognition Cell-matrix Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Cell Communication Protein-containing Complex Binding Regulation Of Multicellular Organismal Process Regulation Of System Process Wound Healing, Spreading Of Epidermal Cells Mesodermal Cell Differentiation Integrin Alpha3-beta1 Complex Integrin Alpha5-beta1 Complex Pyrimidine Nucleoside Transmembrane Transporter Activity Vascular Process In Circulatory System Focal Adhesion Import Into Cell Regulation Of Epithelial Cell Migration Neurotransmitter Reuptake Laminin Binding Cell Adhesion Cell-substrate Adhesion Positive Regulation Of Signaling Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Alpha2-beta1 Complex Putrescine Transmembrane Transporter Activity Virus Receptor Activity Circulatory System Process Regulation Of Biological Quality Positive Regulation Of Protein Localization To Membrane Myoblast Fusion Cell Adhesion Mediated By Integrin Positive Regulation Of Signal Transduction Receptor Complex Wound Healing, Spreading Of Cells Neurotransmitter Uptake Response To Muscle Activity	Membrane Chemoattractant Activity Positive Chemotaxis CCR6 Chemokine Receptor Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Defense Response To Gram-negative Bacterium
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