PPP1R18 and CARD9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPP1R18	CARD9
Gene Name		protein phosphatase 1, regulatory subunit 18	caspase recruitment domain family, member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton	Cytoplasm
	Molecular Function	Actin Binding Phosphatase Binding	Protein Homodimerization Activity CARD Domain Binding
	Biological Process		Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways			Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		37 interactors: CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 SPERT STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52	65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655
Entrez ID		170954	64170
HPRD ID		11172	06236
Ensembl ID		ENSG00000146112	ENSG00000187796
Uniprot IDs		Q6NYC8	Q9H257
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Glycogen Metabolic Process Cell Cycle Polysaccharide Metabolic Process Negative Regulation Of Viral Release From Host Cell Cytoskeleton Organization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Triglyceride Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Viral Transcription Innate Immune Response Entrainment Of Circadian Clock By Photoperiod Regulation Of Viral Release From Host Cell Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Protein Ubiquitination Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Energy Reserve Metabolic Process Organelle Organization Cellular Protein Complex Assembly Protein Modification By Small Protein Conjugation Regulation Of Protein Binding Protein K63-linked Ubiquitination Cellular Macromolecular Complex Assembly Protein Trimerization Establishment Of Chromosome Localization Protein Complex Assembly Embryonic Digestive Tract Development Spliceosomal Complex Disassembly Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Cellular Response To Growth Factor Stimulus Organelle Localization Cellular Localization Cell Division Regulation Of Extrinsic Apoptotic Signaling Pathway Establishment Of Localization In Cell Synapsis Response To Organic Substance Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Homologous Chromosome Segregation Single Organism Reproductive Process Chromosome Segregation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Cellular Carbohydrate Metabolic Process Positive Regulation Of Protein Binding Regulation Of Viral Transcription	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?