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PPP1R18 and NACA
Number of citations of the paper that reports this interaction (PubMedID
30948508
)
59
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, pull down)
PPP1R18
NACA
Description
protein phosphatase 1 regulatory subunit 18
nascent polypeptide associated complex subunit alpha
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytoskeleton
Nucleus
Cytoplasm
Nascent Polypeptide-associated Complex
Extracellular Exosome
Molecular Function
Actin Binding
Protein Binding
Phosphatase Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
Unfolded Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cardiac Ventricle Development
Translation
Protein Targeting To Membrane
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Protein Transport
Wound Healing
Skeletal Muscle Tissue Regeneration
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Skeletal Muscle Tissue Growth
Regulation Of Skeletal Muscle Fiber Development
Heart Trabecula Morphogenesis
Negative Regulation Of Protein Localization To Endoplasmic Reticulum
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Chronic obstructive pulmonary disease (
33909500
)
Hemoglobin levels (
32327693
)
Lung cancer (
28604730
)
Alanine aminotransferase levels (
34315874
)
Aspartate aminotransferase levels (
34315874
)
Asthma (
31619474
)
Atrial fibrillation (
29892015
30061737
)
Diastolic blood pressure (
30224653
)
JT interval (
29874175
)
QRS duration (
30012220
)
Interacting Genes
80 interacting genes:
ABRA
ACTN3
BICD2
CALCOCO2
CARD9
CBY2
CCDC102B
CCDC136
CCDC57
CCDC88B
CDR2L
CEP70
COG6
DES
DZIP1
EIF3L
FAM9B
FHL5
FSD2
GCC1
GFAP
GMCL1
GOLGA2
GOLGA6L9
GOPC
GRIPAP1
GTPBP3
HAP1
HOMER3
HOOK2
HSF2BP
IKZF3
KASH5
KCTD9
KRT13
KRT15
KRT16
KRT19
KRT27
KRT31
KRT33B
KRT34
KRT36
KRT40
LDOC1
LZTS1
LZTS2
MAD1L1
MAPK1
MEOX2
MID2
MRPL38
MTUS2
NACA
NEFL
PDE4DIP
PIBF1
PLEKHF2
PPP1CA
PPP1CC
PPP1R13B
PRPH
SORBS3
SPDL1
STX11
TCF4
TEX11
TFIP11
TRAF2
TRIM23
TRIM27
TRIM54
TRIM62
TRIM69
TSC1
TSGA10
VIM
VPS52
ZMYND12
ZRANB1
17 interacting genes:
APLP1
CCDC90B
FADD
FOS
FUNDC2
IGSF21
JUN
LRIF1
MDM2
PPP1R18
PTEN
SMYD1
SPP1
TBP
TXLNA
UCHL5
ZHX1
Entrez ID
170954
4666
HPRD ID
11172
03137
Ensembl ID
ENSG00000146112
ENSG00000196531
Uniprot IDs
A0A024RCJ8
A0A0G2JHC2
Q6NYC8
E9PAV3
Q13765
PDB IDs
3LKX
3MCB
3MCE
7QWQ
7QWR
7QWS
8P2K
9F1B
9F1C
9F1D
9FQ0
Enriched GO Terms of Interacting Partners
?
Cytoskeleton
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Cytoskeleton Organization
Intermediate Filament
Organelle Organization
Supramolecular Fiber Organization
Structural Constituent Of Skin Epidermis
Keratin Filament
Structural Constituent Of Cytoskeleton
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Intermediate Filament Cytoskeleton
Microtubule-based Process
Centrosome
Morphogenesis Of An Epithelium
Microtubule Cytoskeleton Organization
Tissue Morphogenesis
Cytosol
Cytoplasm
Microtubule Organizing Center
Bergmann Glial Cell Differentiation
Epithelial Cell Differentiation
Microtubule Organizing Center Organization
Negative Regulation Of Viral Transcription
Intracellular Transport
Developmental Process
Regulation Of Viral Transcription
Response To Muramyl Dipeptide
Cellular Developmental Process
Positive Regulation Of Skeletal Muscle Tissue Growth
Establishment Of Localization In Cell
Developmental Process Involved In Reproduction
Establishment Of Protein Localization
Dynein Light Intermediate Chain Binding
Cytoskeleton-dependent Intracellular Transport
Kinetochore Binding
Regulation Of Autophagy
Cell Differentiation
Regulation Of Skeletal Muscle Tissue Growth
Z Disc
Intracellular Protein Localization
Protein Transport
Astrocyte Differentiation
PTW/PP1 Phosphatase Complex
Cellular Localization
Organelle Transport Along Microtubule
Cellular Response To Muramyl Dipeptide
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription Factor AP-1 Complex
Receptor Serine/threonine Kinase Binding
Forebrain Morphogenesis
Response To Steroid Hormone
Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Regulation Of RNA Metabolic Process
Synapse Maturation
Regulation Of Nucleobase-containing Compound Metabolic Process
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Response To Immobilization Stress
Response To Muscle Stretch
SMAD Protein Signal Transduction
R-SMAD Binding
Negative Regulation Of Neuron Projection Development
Regulation Of Primary Metabolic Process
Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Proteolysis
Alpha-2B Adrenergic Receptor Binding
Developmental Process
Response To Mechanical Stimulus
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Medium-term Memory
Integrated Stress Response Signaling
Cellular Response To Prolactin
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Enzyme Binding
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Response To Formaldehyde
Cellular Response To Vitamin B1
Response To Cocaine
Negative Regulation Of Cell Projection Organization
Negative Regulation Of Synaptic Vesicle Clustering
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation
Positive Regulation Of Proteolysis
Positive Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Axonogenesis
Cell Death
Apoptotic Process
Cytosolic MRNA Polyadenylation
Alpha-2C Adrenergic Receptor Binding
Animal Organ Development
Programmed Cell Death
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Tagcloud (Intersection)
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