FEZ2 and SCOC

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		FEZ2	SCOC
Gene Name		fasciculation and elongation protein zeta 2 (zygin II)	short coiled-coil protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Golgi Membrane Endosome Trans-Golgi Network Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance	Positive Regulation Of Macroautophagy
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251	8 interactors: ARL1 FEZ1 FEZ2 ITSN1 KRT40 MAPK8 SCHIP1 TCF4
Entrez ID		9637	60592
HPRD ID		09213	18027
Ensembl ID		ENSG00000171055	ENSG00000153130
Uniprot IDs		Q9UHY8	Q9UIL1
PDB IDs			4BWD
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production	Response To External Stimulus Axon Guidance Organelle Localization Positive Regulation Of Protein Kinase B Signaling Axonogenesis Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Chemotaxis Generation Of Neurons Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Death Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Neuron Projection Morphogenesis Neurogenesis Regulation Of Protein Binding Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Cell Morphogenesis Involved In Differentiation Cell Development Maintenance Of DNA Repeat Elements Neuron Projection Development JUN Phosphorylation Cell Projection Morphogenesis Establishment Of Localization In Cell Cell Part Morphogenesis Vesicle Localization Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Deacetylase Activity Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Negative Regulation Of Programmed Cell Death Embryonic Genitalia Morphogenesis Neuron Development Positive Regulation Of Intracellular Transport Negative Regulation Of Cell Death Positive Regulation Of Determination Of Dorsal Identity Myoblast Fate Commitment Nervous System Development Regulation Of Binding Cellular Response To Stimulus Positive Regulation Of Hydrolase Activity Secretory Granule Localization Cell Morphogenesis Ossification
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