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NEK1 and ZNF350
Number of citations of the paper that reports this interaction (PMID
14690447
)
15
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NEK1
ZNF350
Gene Name
NIMA-related kinase 1
zinc finger protein 350
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Pericentriolar Material
Nucleus
Cytoplasm
Centrosome
Nucleus
Nucleoplasm
Nuclear Matrix
Transcriptional Repressor Complex
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
MAPK Cascade
Activation Of MAPK Activity
Cellular Response To DNA Damage Stimulus
Mitotic Nuclear Division
Response To Ionizing Radiation
Peptidyl-tyrosine Phosphorylation
Cilium Assembly
Cell Division
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription, DNA-templated
Pathways
Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
ATRX
CSN2
CTNNAL1
EXOSC4
FEZ1
FEZ2
KIF3A
MRE11A
PPP2R5A
TP53BP1
TSC2
YWHAH
ZNF350
4 interactors:
ATF7IP
BRCA1
NEK1
RNF11
Entrez ID
4750
59348
HPRD ID
06847
05663
Ensembl ID
ENSG00000137601
ENSG00000256683
Uniprot IDs
Q5JXL9
Q96PY6
Q9GZX5
PDB IDs
4APC
4B9D
Enriched GO Terms of Interacting Partners
?
Response To Stimulus
Regulation Of Cellular Component Organization
Cellular Response To Stimulus
Negative Regulation Of Cellular Metabolic Process
Nervous System Development
Regulation Of Cellular Process
DNA Recombination
Glucocorticoid Catabolic Process
Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter
Regulation Of Dendrite Morphogenesis
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Generation Of Neurons
DNA Modification
Neurogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Dendrite Development
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Lipid Kinase Activity
Cellular Response To Hydroxyurea
DNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Epidermal Stem Cell Homeostasis
Regulation Of DNA Replication
Signal Transduction
Neuron Differentiation
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Nuclear Cell Cycle DNA Replication
Protein Transport Into Plasma Membrane Raft
Cell Projection Organization
Double-strand Break Repair
System Development
Regulation Of Mitotic Recombination
Plus-end-directed Vesicle Transport Along Microtubule
Protein Localization To Plasma Membrane Raft
Regulation Of Transcription, DNA-templated
Nuclear MRNA Surveillance
DNA Repair
Chemotaxis
Signaling
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Cell Communication
Positive Regulation Of Transcription, DNA-templated
Regulation Of Endocytosis
Regulation Of RNA Metabolic Process
Cullin Deneddylation
Protein Autoubiquitination
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Response To Ionizing Radiation
Positive Regulation Of Histone H3-K9 Acetylation
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Cellular Response To Indole-3-methanol
Negative Regulation Of Centriole Replication
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Protein K6-linked Ubiquitination
Negative Regulation Of Histone H3-K9 Methylation
Positive Regulation Of Histone H3-K9 Methylation
Dosage Compensation
Regulation Of Histone H3-K9 Acetylation
Regulation Of Centriole Replication
Positive Regulation Of Histone H3-K4 Methylation
Regulation Of Histone H4 Acetylation
Negative Regulation Of Fatty Acid Biosynthetic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Response To Radiation
DNA Damage Response, Signal Transduction Resulting In Transcription
Negative Regulation Of Histone Methylation
Negative Regulation Of Centrosome Duplication
Regulation Of DNA Methylation
Negative Regulation Of Histone Acetylation
Positive Regulation Of Histone Acetylation
Negative Regulation Of Peptidyl-lysine Acetylation
Regulation Of Histone H3-K4 Methylation
Protein Ubiquitination
Negative Regulation Of Protein Acetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Postreplication Repair
Positive Regulation Of Protein Acetylation
Protein Modification By Small Protein Conjugation
Regulation Of Transcription From RNA Polymerase III Promoter
Regulation Of DNA-templated Transcription, Initiation
Negative Regulation Of Fatty Acid Metabolic Process
Regulation Of Gene Expression By Genetic Imprinting
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Cellular Metabolic Process
Genetic Imprinting
Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Vascular Endothelial Growth Factor Production
G2 DNA Damage Checkpoint
Positive Regulation Of Histone Methylation
Positive Regulation Of DNA Repair
Androgen Receptor Signaling Pathway
Tagcloud
?
axin
cdk1
crb3
dock7
dsh
ezrin
fip200
gadd34
gsk3
hamartin
herc1
hscp
immunoprecipitate
melted
merlin
moesin
nade
p27kip1
p75ntr
pam
patj
pc1
pp2ac
rabaptin
radixin
rheb
rsk1
tbc7
tuberin
Tagcloud (Difference)
?
axin
cdk1
crb3
dock7
dsh
ezrin
fip200
gadd34
gsk3
hamartin
herc1
hscp
immunoprecipitate
melted
merlin
moesin
nade
p27kip1
p75ntr
pam
patj
pc1
pp2ac
rabaptin
radixin
rheb
rsk1
tbc7
tuberin
Tagcloud (Intersection)
?