RAB3GAP1

Gene Name		RAB3 GTPase activating protein subunit 1 (catalytic)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Protein Complex Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network
	Molecular Function	Rab GTPase Activator Activity Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Brain Development Hypothalamus Development Positive Regulation Of Rab GTPase Activity Lipid Particle Organization Camera-type Eye Development Regulation Of GTPase Activity Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Excitatory Postsynaptic Membrane Potential Face Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Corneal structure ( 21979947)
Protein-protein Interactions		8 interactors: FEZ1 FEZ2 RAB22A RAB39A RAB39B RAB3GAP2 RPH3AL WDR7
Entrez ID		22930
HPRD ID		16002
Ensembl ID		ENSG00000115839
Uniprot IDs		B9A6J2 C9J837 Q15042
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Ras Protein Signal Transduction Establishment Of Protein Localization Intracellular Transport Protein Localization Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Vesicle Size Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Phagosome-lysosome Fusion Transport Phagosome Acidification Negative Regulation Of Macroautophagy Phagolysosome Assembly Establishment Of Mitochondrion Localization Intracellular PH Reduction Axon Guidance PH Reduction
Tagcloud ?		acidic adaptor anchored binds catalytic compartment consists envelope ergic etc execute ff ffat golgi gtpase heterodimer motif phenylalanines potently recruit reduces substitution tail traffic vap vesicle