TAF6 and GTF2E1

Number of citations of the paper that reports this interaction (PMID 7667268)
20

Data Source:
HPRD (in vitro)

		TAF6	GTF2E1
Gene Name		TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	general transcription factor IIE, polypeptide 1, alpha 56kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity	Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Gene Expression Viral Process Negative Regulation Of Cell Cycle Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		24 interactors: AHR APP CIITA GTF2E1 HIST3H3 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9 TAF9B	28 interactors: AES APP CBFA2T2 CDK7 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F2 GTF2H1 GTF2H4 IKBKG MDM2 PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBP TCEA1 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1
Entrez ID		6878	2960
HPRD ID		11807	01799
Ensembl ID		ENSG00000106290	ENSG00000153767
Uniprot IDs		P49848	P29083
PDB IDs			1VD4 2JTX 2RNQ 2RNR
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Cellular Process Peptidyl-lysine Modification Rhythmic Process Histone H3 Acetylation Chromatin Modification Metabolic Process Histone Modification Chromosome Organization Chromatin Organization Negative Regulation Of Transcription, DNA-templated	Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Viral Process DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Positive Regulation Of Viral Process Positive Regulation Of Viral Transcription Regulation Of Viral Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process 7-methylguanosine MRNA Capping Positive Regulation Of Cellular Biosynthetic Process 7-methylguanosine RNA Capping Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase I Promoter Nucleotide-excision Repair Positive Regulation Of Metabolic Process Regulation Of Cellular Process Nucleotide-excision Repair, DNA Damage Removal Positive Regulation Of Transcription, DNA-templated MRNA Processing DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined	avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?		acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined	avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?