TAF6 and TAF8

Number of citations of the paper that reports this interaction (PubMedID 14580349)
0

Data Source:
HPRD (in vitro, in vivo)

		TAF6	TAF8
Description		TATA-box binding protein associated factor 6	TATA-box binding protein associated factor 8
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex MLL1 Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of DNA Repair DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Apoptotic Process Negative Regulation Of Cell Population Proliferation MRNA Transcription By RNA Polymerase II Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	DNA-templated Transcription Open Complex Formation Inner Cell Mass Cell Proliferation Transcription Initiation At RNA Polymerase II Promoter Cell Differentiation MRNA Transcription By RNA Polymerase II Regulation Of Fat Cell Differentiation RNA Polymerase II Preinitiation Complex Assembly Maintenance Of Protein Location In Nucleus Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (number of eye fixations) ( 26242244) Exploratory eye movement dysfunction in schizophrenia (responsive search score) ( 26242244) HDL cholesterol levels ( 28334899) Hemoglobin levels ( 33491795) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		26 interacting genes: AHR APP BANP BTG3 CIITA GTF2E1 H3-4 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 PIH1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9	13 interacting genes: H3-4 KPNA2 KPNB1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF7 TAF9
Entrez ID		6878	129685
HPRD ID		11807	18167
Ensembl ID		ENSG00000106290	ENSG00000137413
Uniprot IDs		A4D299 P49848	A0A8I5KXI2 A0A8I5QL44 Q7Z7C8
PDB IDs		5FUR 6F3T 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	4WV4 4WV6 5FUR 6MZC 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGG 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Transcription Factor TFTC Complex Protein-DNA Complex Assembly Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein Heterodimerization Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process DNA Binding Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Nucleus Protein-containing Complex Assembly Positive Regulation Of Metabolic Process MRNA Metabolic Process Nucleic Acid Metabolic Process Protein-containing Complex Organization CCAAT-binding Factor Complex Regulation Of DNA Repair TBP-class Protein Binding MLL1 Complex Chromatin Regulation Of Gene Expression DNA-binding Transcription Factor Binding Regulation Of Macromolecule Biosynthetic Process	Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Factor TFTC Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Protein-DNA Complex Assembly Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA Repair MRNA Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Organization MLL1 Complex Regulation Of DNA Metabolic Process Protein Heterodimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of RNA Metabolic Process Cellular Component Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process SAGA Complex Regulation Of Cellular Response To Stress Positive Regulation Of Transcription By RNA Polymerase II RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of Biosynthetic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process TBP-class Protein Binding Histone Acetyltransferase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Male Germ Cell Nucleus Aryl Hydrocarbon Receptor Binding
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