GOSR2 and STX5

Number of citations of the paper that reports this interaction (PMID 9094723)
54

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		GOSR2	STX5
Gene Name		golgi SNAP receptor complex member 2	syntaxin 5
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity	SNARE Binding SNAP Receptor Activity Protein Binding Protein N-terminus Binding
	Biological Process	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process Vesicle Fusion With Golgi Apparatus Membrane Fusion	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Systolic blood pressure ( 21909115) Ventricular conduction ( 21076409)
Protein-Protein Interactions		10 interactors: APP ARF1 CCDC155 GOLGA8EP GOLGA8F NAPA STX4 STX5 STX6 USO1	27 interactors: APLP1 ASNA1 BAG6 BET1 CCDC155 COPS6 GOSR1 GOSR2 HAP1 IMMT LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 TACC1 TP53 USO1 VAPB VCP VCPIP1
Entrez ID		9570	6811
HPRD ID		04937	04426
Ensembl ID		ENSG00000108433	ENSG00000162236
Uniprot IDs		I3L4Z6 O14653	B4DKR0 F8W8Q9 Q13190
PDB IDs		3EG9	3EFO
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Membrane Fusion Vesicle Fusion Vesicle Organization Establishment Of Localization In Cell Organelle Fusion Cellular Localization Vesicle-mediated Transport Intracellular Transport Membrane Organization Protein Transport Establishment Of Protein Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Membrane Docking Intracellular Protein Transport Protein Localization Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Protein Localization Regulation Of Synaptic Transmission Transport Organelle Organization Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Organelle Localization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis ER To Golgi Vesicle-mediated Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Golgi Vesicle Docking SNARE Complex Disassembly Collateral Sprouting In Absence Of Injury Golgi Disassembly Transition Metal Ion Homeostasis Regulation Of Exocytosis Regulation Of Synaptic Plasticity Collateral Sprouting Axon Midline Choice Point Recognition Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Vesicle Priming Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Axon Choice Point Recognition Golgi Ribbon Formation	Membrane Fusion Golgi Vesicle Transport Membrane Organization Cellular Localization Organelle Fusion Vesicle-mediated Transport Establishment Of Protein Localization ER To Golgi Vesicle-mediated Transport Vesicle Fusion Establishment Of Localization In Cell Intracellular Transport Protein Localization Protein Transport Vesicle Organization Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Organelle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Transport Cytoplasmic Transport Response To Endoplasmic Reticulum Stress SNARE Complex Disassembly Vesicle Docking Membrane Docking Organelle Localization ER-nucleus Signaling Pathway Cellular Protein Localization Endoplasmic Reticulum Organization Double-strand Break Repair Establishment Of Organelle Localization Exocytosis Protein Insertion Into ER Membrane Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Intracellular Protein Transport Synaptic Vesicle Priming Negative Regulation Of Macroautophagy Establishment Of Vesicle Localization Vesicle Localization Endomembrane System Organization Cellular Component Assembly Response To Stress Endoplasmic Reticulum Unfolded Protein Response Brain Development Cellular Response To Stress Cellular Response To Unfolded Protein Head Development Secretion By Cell Protein Insertion Into Membrane Neurotransmitter Secretion
Tagcloud ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl
Tagcloud (Difference) ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl
Tagcloud (Intersection) ?