GOSR2 and USO1

Number of citations of the paper that reports this interaction (PMID 11927603)
54

Data Source:
HPRD (in vitro)

		GOSR2	USO1
Gene Name		golgi SNAP receptor complex member 2	USO1 vesicle transport factor
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane	Golgi Membrane Nucleolus Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity	Protein Transporter Activity Poly(A) RNA Binding
	Biological Process	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process Vesicle Fusion With Golgi Apparatus Membrane Fusion	Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Transcytosis Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)	Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Systolic blood pressure ( 21909115) Ventricular conduction ( 21076409)
Protein-Protein Interactions		10 interactors: APP ARF1 CCDC155 GOLGA8EP GOLGA8F NAPA STX4 STX5 STX6 USO1	24 interactors: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6
Entrez ID		9570	8615
HPRD ID		04937	09135
Ensembl ID		ENSG00000108433	ENSG00000138768
Uniprot IDs		I3L4Z6 O14653	O60763
PDB IDs		3EG9	2W3C
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Membrane Fusion Vesicle Fusion Vesicle Organization Establishment Of Localization In Cell Organelle Fusion Cellular Localization Vesicle-mediated Transport Intracellular Transport Membrane Organization Protein Transport Establishment Of Protein Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Membrane Docking Intracellular Protein Transport Protein Localization Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Protein Localization Regulation Of Synaptic Transmission Transport Organelle Organization Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Organelle Localization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis ER To Golgi Vesicle-mediated Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Golgi Vesicle Docking SNARE Complex Disassembly Collateral Sprouting In Absence Of Injury Golgi Disassembly Transition Metal Ion Homeostasis Regulation Of Exocytosis Regulation Of Synaptic Plasticity Collateral Sprouting Axon Midline Choice Point Recognition Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Vesicle Priming Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Axon Choice Point Recognition Golgi Ribbon Formation	Membrane Fusion Golgi Vesicle Transport Vesicle-mediated Transport Vesicle Organization Membrane Organization Retrograde Transport, Endosome To Golgi Vesicle Docking Membrane Docking ER To Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Transport Establishment Of Localization In Cell Cytoplasmic Transport Vesicle Fusion Protein Transport Establishment Of Protein Localization Cellular Localization Organelle Fusion Golgi Organization Establishment Of Vesicle Localization Post-Golgi Vesicle-mediated Transport Vesicle Localization Endomembrane System Organization Protein Localization Transport Organelle Organization Positive Regulation Of Protein Metabolic Process Establishment Of Organelle Localization Vesicle Docking Involved In Exocytosis Positive Regulation Of Metabolic Process Intra-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion With Golgi Apparatus Organelle Localization Positive Regulation Of Cellular Metabolic Process Secretion By Cell Exocytosis Secretion Regulation Of Cellular Localization Cell Morphogenesis Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Vesicle Endocytosis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Synaptic Vesicle Recycling Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Regulation Of Kinase Activity
Tagcloud ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34
Tagcloud (Difference) ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	absorbed altogether autophagosomes biogenesis coat compartment copi copii cups endosomal enter exit export golgi grh1 pik1 relocates relocation return sec7 secrete sed5 snare sort starvation tethering unconventional vacuole vps34
Tagcloud (Intersection) ?