GOSR2 and NAPA

Number of citations of the paper that reports this interaction (PMID 9349823)
11

Data Source:
HPRD (in vivo, in vitro)

		GOSR2	NAPA
Gene Name		golgi SNAP receptor complex member 2	N-ethylmaleimide-sensitive factor attachment protein, alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane	Vacuolar Membrane Cytosol Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding Transporter Activity SNAP Receptor Activity	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process Vesicle Fusion With Golgi Apparatus Membrane Fusion	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Neuron Differentiation Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization Membrane Organization Membrane Fusion
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Systolic blood pressure ( 21909115) Ventricular conduction ( 21076409)
Protein-Protein Interactions		10 interactors: APP ARF1 CCDC155 GOLGA8EP GOLGA8F NAPA STX4 STX5 STX6 USO1	17 interactors: APP BNIP1 GNA12 GOSR1 GOSR2 NSF RTN4 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8
Entrez ID		9570	8775
HPRD ID		04937	04447
Ensembl ID		ENSG00000108433	ENSG00000105402
Uniprot IDs		I3L4Z6 O14653	P54920
PDB IDs		3EG9
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Membrane Fusion Vesicle Fusion Vesicle Organization Establishment Of Localization In Cell Organelle Fusion Cellular Localization Vesicle-mediated Transport Intracellular Transport Membrane Organization Protein Transport Establishment Of Protein Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Membrane Docking Intracellular Protein Transport Protein Localization Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Protein Localization Regulation Of Synaptic Transmission Transport Organelle Organization Establishment Of Organelle Localization Regulation Of Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Organelle Localization Golgi Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis ER To Golgi Vesicle-mediated Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Golgi Vesicle Docking SNARE Complex Disassembly Collateral Sprouting In Absence Of Injury Golgi Disassembly Transition Metal Ion Homeostasis Regulation Of Exocytosis Regulation Of Synaptic Plasticity Collateral Sprouting Axon Midline Choice Point Recognition Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Vesicle Priming Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Axon Choice Point Recognition Golgi Ribbon Formation	Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Organization Membrane Organization Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Localization In Cell Intracellular Transport Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Localization Protein Transport Golgi Vesicle Transport Establishment Of Protein Localization Exocytosis Post-Golgi Vesicle-mediated Transport Transport Protein Localization Secretion By Cell Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Intracellular Protein Transport Organelle Organization Secretion Regulation Of Cellular Localization Neurotransmitter Secretion Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Intra-Golgi Vesicle-mediated Transport Organelle Localization Platelet Activation Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Regulation Of Protein Localization Endosomal Transport Vesicle Localization Retrograde Transport, Endosome To Golgi Synaptic Vesicle Docking Vesicle Fusion With Golgi Apparatus SNARE Complex Assembly Synaptic Vesicle Priming Regulation Of Hormone Secretion Regulation Of Body Fluid Levels ER To Golgi Vesicle-mediated Transport Synaptic Transmission
Tagcloud ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Difference) ?		430g bounding came cavus clonic clue creatine deformities discharges electroencephalography epilepsies founder g144w myoclonic myoclonus norway pes photosensitivity predominance ready relentless scoliosis seizures snap spike syndactyly tonic uniformly wheelchair	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Intersection) ?