SPAG7 and LXN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPAG7	LXN
Description		sperm associated antigen 7	latexin
Image
GO Annotations	Cellular Component	Nucleus	Extracellular Space Cytoplasm
	Molecular Function	Nucleic Acid Binding Protein Binding	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity
	Biological Process		Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Pathways
Drugs
Diseases
GWAS		Keratoconus ( 33649486) Mean platelet volume ( 27863252) Serum metabolite levels ( 33031748)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		2 interacting genes: ABHD16A LXN	25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679
Entrez ID		9552	56925
HPRD ID		10247	14327
Ensembl ID		ENSG00000091640	ENSG00000079257
Uniprot IDs		O75391	Q9BS40
PDB IDs		2CPM	2BO9
Enriched GO Terms of Interacting Partners?		3',5'-cGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity Organophosphate Catabolic Process Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Cellular Response To CGMP 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP Metabolic Process Cyclic Nucleotide Catabolic Process Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cellular Response To Macrophage Colony-stimulating Factor Stimulus Response To Macrophage Colony-stimulating Factor Negative Regulation Of CGMP-mediated Signaling 3',5'-cyclic-GMP Phosphodiesterase Activity Phosphate Ion Binding Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus CAMP Binding CGMP Catabolic Process TPR Domain Binding Regulation Of CGMP-mediated Signaling Monocyte Differentiation 3',5'-cyclic-nucleotide Phosphodiesterase Activity Response To 2,3,7,8-tetrachlorodibenzodioxine CGMP Binding Positive Regulation Of Vascular Permeability Negative Regulation Of Vascular Permeability Response To CGMP Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Monoacylglycerol Lipase Activity Phosphatidylserine Metabolic Process Monoacylglycerol Catabolic Process Phosphatidylcholine Lysophospholipase Activity Metalloendopeptidase Inhibitor Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Temperature Stimulus Involved In Sensory Perception Heart Valve Development Glycerophospholipid Catabolic Process Detection Of Temperature Stimulus Negative Regulation Of CAMP/PKA Signal Transduction Phospholipase Activity Acylglycerol Catabolic Process CGMP-mediated Signaling Modified Amino Acid Catabolic Process Aorta Development Ventricular Septum Development Establishment Of Endothelial Barrier Cyclic Purine Nucleotide Metabolic Process Organophosphate Metabolic Process Artery Development Cardiac Septum Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?