LXN and ZNF679

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LXN	ZNF679
Description		latexin	zinc finger protein 679
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Response to statin therapy ( 20339536) Rheumatoid arthritis ( 30891314)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	6 interacting genes: KRTAP10-3 KRTAP10-5 KRTAP10-6 LXN MDFI TP53
Entrez ID		56925	168417
HPRD ID		14327	14621
Ensembl ID		ENSG00000079257	ENSG00000197123
Uniprot IDs		Q9BS40	Q8IYX0
PDB IDs		2BO9
Enriched GO Terms of Interacting Partners?			Keratin Filament Intermediate Filament Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity B Cell Lineage Commitment Regulation Of Pentose-phosphate Shunt Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence
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