LXN and ZNF430

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LXN	ZNF430
Description		latexin	zinc finger protein 430
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Substantia Nigra Development
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	2 interacting genes: HGS LXN
Entrez ID		56925	80264
HPRD ID		14327	15788
Ensembl ID		ENSG00000079257	ENSG00000118620
Uniprot IDs		Q9BS40	A8K360 Q2NKJ9 Q9H8G1
PDB IDs		2BO9
Enriched GO Terms of Interacting Partners?			Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway ESCRT-0 Complex Multivesicular Body Membrane Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Phagocytic Vesicle Lumen Multivesicular Body Organization Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Protein Targeting To Lysosome Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Exosomal Secretion Ubiquitin-like Protein Ligase Binding Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Multivesicular Body Assembly Negative Regulation Of Receptor Signaling Pathway Via STAT Positive Regulation Of Exosomal Secretion Metalloendopeptidase Inhibitor Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Temperature Stimulus Involved In Sensory Perception Detection Of Temperature Stimulus Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Membrane Invagination Multivesicular Body Sorting Pathway Protein Targeting To Vacuole Protein Localization To Lysosome Enzyme Inhibitor Activity Regulation Of MAP Kinase Activity Establishment Of Protein Localization To Vacuole Receptor Internalization Regulation Of Receptor Signaling Pathway Via JAK-STAT Endocytic Recycling Positive Regulation Of Exocytosis Endosome Organization Protein Localization To Vacuole
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