SPAG7 and ABHD16A

Number of citations: 0 (PubMedID 14667819)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		SPAG7	ABHD16A
Name		sperm associated antigen 7	abhydrolase domain containing 16A, phospholipase
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus	Membrane
	Molecular Function	Nucleic Acid Binding Protein Binding	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Monoacylglycerol Lipase Activity
	Biological Process	None	Lipid Metabolic Process Phosphatidylserine Catabolic Process Monoacylglycerol Catabolic Process Prostaglandin Catabolic Process
GWAS		Keratoconus ( 33649486 ) Mean platelet volume ( 27863252 ) Serum metabolite levels ( 33031748 )	Asthma ( 31619474 ) Asthma (childhood onset) ( 31619474 ) Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Inflammatory bowel disease ( 28067908 ) Malaria ( 31844061 ) Monocyte percentage of white cells ( 32888494 ) Ulcerative colitis ( 28067908 )
Novel Interactors		1 novel interactors: PDE2A	None recorded
Interacting Genes		2 interacting genes: ABHD16A LXN	69 interacting genes: AGPAT3 AQP6 AQP7 ATP5MC3 ATP5PF BRI3 CBARP CIDEB CREB3 CYP1A2 DNAJC1 DTX2 EBP ERGIC3 FDPS FKBP7 GDAP1 GJA5 GOLT1A GORAB GPR152 GPRC5C GYPC HM13 HNRNPA1 HSD17B13 IFITM1 IFITM3 ITGAM LTA MLH1 MT-ND3 MT-ND4 PERP PILRB PKMYT1 POLE PRAF2 PTGS2 RETREG3 RHBDD2 RHBDL1 RNF5 SAFB SEC22B SERF1A SERF1B SLC10A1 SLC30A2 SLC7A8 SPAG4 SPAG7 STMN4 STX1B TM4SF19 TMEM139 TMEM143 TMEM147 TMEM14B TMEM222 TMEM237 TMEM31 TMEM65 TSPAN2 UNC93A UPF1 VAMP5 VMA21 WBP1L
Entrez ID		9552	7920
HPRD ID		10247	15929
Ensembl ID		ENSG00000091640	ENSG00000204427
Uniprot IDs		O75391	A0A1U9X777 B3KNX9 O95870
PDB IDs		2CPM	Not available
GO Terms Enriched among Interactors		3',5'-cGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity Organophosphate Catabolic Process Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Cellular Response To CGMP 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP Metabolic Process Cyclic Nucleotide Catabolic Process Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cellular Response To Macrophage Colony-stimulating Factor Stimulus Response To Macrophage Colony-stimulating Factor Negative Regulation Of CGMP-mediated Signaling 3',5'-cyclic-GMP Phosphodiesterase Activity Phosphate Ion Binding Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus CAMP Binding CGMP Catabolic Process TPR Domain Binding Regulation Of CGMP-mediated Signaling Monocyte Differentiation 3',5'-cyclic-nucleotide Phosphodiesterase Activity Response To 2,3,7,8-tetrachlorodibenzodioxine CGMP Binding Positive Regulation Of Vascular Permeability Negative Regulation Of Vascular Permeability Response To CGMP Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Monoacylglycerol Lipase Activity Phosphatidylserine Metabolic Process Monoacylglycerol Catabolic Process Phosphatidylcholine Lysophospholipase Activity Metalloendopeptidase Inhibitor Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Temperature Stimulus Involved In Sensory Perception Heart Valve Development Glycerophospholipid Catabolic Process Detection Of Temperature Stimulus Negative Regulation Of CAMP/PKA Signal Transduction Phospholipase Activity Acylglycerol Catabolic Process CGMP-mediated Signaling Modified Amino Acid Catabolic Process Aorta Development Ventricular Septum Development Establishment Of Endothelial Barrier Cyclic Purine Nucleotide Metabolic Process Organophosphate Metabolic Process Artery Development Cardiac Septum Development	Membrane Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum