LXN and CYBC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LXN	CYBC1
Description		latexin	cytochrome b-245 chaperone 1
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity	Protein Binding
	Biological Process	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Immune System Process Innate Immune Response Respiratory Burst After Phagocytosis
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	65 interacting genes: ADIPOQ AGTRAP AHNAK2 AIG1 APCDD1L APOA2 APOL2 AQP10 AQP6 AQP8 ARLN BET1 C14orf180 CD53 CISD2 CLDN7 CLN6 COQ9 CPLX4 CREB3 CREB3L1 CYBB ERGIC3 ETS1 FAM209A GJA8 GPR151 GPR152 GPX8 HSD17B11 HSD17B13 INSIG2 JAGN1 KASH5 KIR2DL3 LAT LMNA LXN MFF MGST3 MTIF3 NINJ2 NOX3 NRM P2RX1 PDZK1IP1 PEX12 PLIN3 PLP1 PLP2 SCD SHISA4 SLC35H1 SLC71A2 SPN SSMEM1 STX2 THBD TM4SF19 TMEM128 TMEM80 TMPRSS2 TMX2 TRAM1L1 TSPAN12
Entrez ID		56925	79415
HPRD ID		14327	14630
Ensembl ID		ENSG00000079257	ENSG00000178927
Uniprot IDs		Q9BS40	Q9BQA9
PDB IDs		2BO9	8KEI
Enriched GO Terms of Interacting Partners?			Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Water Channel Activity Channel Activity Negative Regulation Of Cholesterol Import Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On NAD(P)H, Oxygen As Acceptor Regulation Of Cholesterol Import One-carbon Compound Transport Water Transport Superoxide-generating NADPH Oxidase Activity Identical Protein Binding Fluid Transport Lipid Droplet Ammonium Channel Activity Urea Transmembrane Transport
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