SPAG7

Description		sperm associated antigen 7
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GO Annotations	Cellular Component	Nucleus
	Molecular Function	Nucleic Acid Binding Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Keratoconus ( 33649486) Mean platelet volume ( 27863252) Serum metabolite levels ( 33031748)
Novel Interacting Genes		1 novel interacting genes: PDE2A
Interacting Genes		2 interacting genes: ABHD16A LXN
Entrez ID		9552
HPRD ID		10247
Ensembl ID		ENSG00000091640
Uniprot IDs		O75391
PDB IDs		2CPM
Enriched GO Terms of Interacting Partners?		3',5'-cGMP-stimulated Cyclic-nucleotide Phosphodiesterase Activity Organophosphate Catabolic Process Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Cellular Response To CGMP 3',5'-cyclic-AMP Phosphodiesterase Activity CGMP Metabolic Process Cyclic Nucleotide Catabolic Process Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cellular Response To Macrophage Colony-stimulating Factor Stimulus Response To Macrophage Colony-stimulating Factor Negative Regulation Of CGMP-mediated Signaling 3',5'-cyclic-GMP Phosphodiesterase Activity Phosphate Ion Binding Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus CAMP Binding CGMP Catabolic Process TPR Domain Binding Regulation Of CGMP-mediated Signaling Monocyte Differentiation 3',5'-cyclic-nucleotide Phosphodiesterase Activity Response To 2,3,7,8-tetrachlorodibenzodioxine CGMP Binding Positive Regulation Of Vascular Permeability Negative Regulation Of Vascular Permeability Response To CGMP Negative Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Monoacylglycerol Lipase Activity Phosphatidylserine Metabolic Process Monoacylglycerol Catabolic Process Phosphatidylcholine Lysophospholipase Activity Metalloendopeptidase Inhibitor Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Temperature Stimulus Involved In Sensory Perception Heart Valve Development Glycerophospholipid Catabolic Process Detection Of Temperature Stimulus Negative Regulation Of CAMP/PKA Signal Transduction Phospholipase Activity Acylglycerol Catabolic Process CGMP-mediated Signaling Modified Amino Acid Catabolic Process Aorta Development Ventricular Septum Development Establishment Of Endothelial Barrier Cyclic Purine Nucleotide Metabolic Process Organophosphate Metabolic Process Artery Development Cardiac Septum Development
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