LXN and PPP1R3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LXN	PPP1R3C
Description		latexin	protein phosphatase 1 regulatory subunit 3C
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GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Protein Phosphatase Type 1 Complex Cytosol
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Binding Molecular Adaptor Activity Glycogen Binding
	Biological Process	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Glycogen Metabolic Process Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	10 interacting genes: APP EPM2A LONRF1 LXN NHLRC1 PPP1CA PPP1CB PPP1CC PRKAB2 SGTA
Entrez ID		56925	5507
HPRD ID		14327	04298
Ensembl ID		ENSG00000079257	ENSG00000119938
Uniprot IDs		Q9BS40	Q9UQK1
PDB IDs		2BO9	7QF7 7QFA 7QFB 7QM2
Enriched GO Terms of Interacting Partners?			Glycogen Metabolic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process PTW/PP1 Phosphatase Complex Energy Derivation By Oxidation Of Organic Compounds Phosphatase Activity Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Dephosphorylation Generation Of Precursor Metabolites And Energy Phosphoprotein Phosphatase Activity Carbohydrate Metabolic Process Circadian Regulation Of Gene Expression Protein Metabolic Process Response To Light Stimulus Regulation Of Circadian Rhythm Glycogen Biosynthetic Process Response To Lead Ion Transition Metal Ion Binding Circadian Rhythm Polysaccharide Biosynthetic Process Perikaryon Protein Phosphatase 1 Binding Dendritic Spine Response To Radiation Chromosome, Telomeric Region Protein Kinase Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Hydrolase Activity Myosin-light-chain-phosphatase Activity Carbohydrate Phosphatase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Rhythmic Process Cytosol Positive Regulation Of Gliogenesis Regulation Of Carbohydrate Catabolic Process Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import
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