LXN and MCMDC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LXN	MCMDC2
Description		latexin	minichromosome maintenance domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity	DNA Binding Protein Binding ATP Binding
	Biological Process	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Double-strand Break Repair Via Break-induced Replication DNA Repair DNA Damage Response Synaptonemal Complex Assembly Meiotic Recombination Nodule Assembly Spermatogenesis Late Meiotic Recombination Nodule Assembly Oogenesis Meiotic Cell Cycle Double-strand Break Repair Involved In Meiotic Recombination
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	1 interacting genes: LXN
Entrez ID		56925	157777
HPRD ID		14327	08072
Ensembl ID		ENSG00000079257	ENSG00000178460
Uniprot IDs		Q9BS40	B4DXX4 Q4G0Z9
PDB IDs		2BO9
Enriched GO Terms of Interacting Partners?			Metalloendopeptidase Inhibitor Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Temperature Stimulus Involved In Sensory Perception Detection Of Temperature Stimulus Enzyme Inhibitor Activity Peptidase Inhibitor Activity Heparin Binding Response To Temperature Stimulus Detection Of Abiotic Stimulus Detection Of Stimulus Involved In Sensory Perception Detection Of Stimulus
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