BAG2 and WDR77

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		BAG2	WDR77
Description		BAG cochaperone 2	WD repeat domain 77
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Axon Dendrite Protein Folding Chaperone Complex Dendritic Microtubule	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cul4B-RING E3 Ubiquitin Ligase Complex Methylosome Transferase Complex
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Transmembrane Transporter Binding Tau Protein Binding Protein-folding Chaperone Binding	Transcription Coactivator Activity Protein Binding Methyl-CpG Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Protein Stabilization Positive Regulation Of Proteasomal Protein Catabolic Process	Protein Polyubiquitination Spliceosomal SnRNP Assembly Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Oocyte Axis Specification Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of MRNA Splicing, Via Spliceosome Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways		Regulation of HSF1-mediated heat shock response	snRNP Assembly RMTs methylate histone arginines
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: CCAR2 DAPK1 DISC1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83	46 interacting genes: AQR BAG2 CDK19 CDK8 CLNS1A CREBBP CTDP1 EIF4A1 GLI1 GPKOW H2AC21 HNRNPM LSM3 NKX3-1 PCBP2 PDCD4 PPIL1 PPP1R8 PQBP1 PRKG1 PRKG2 PRMT5 QKI RBM5 SAP30BP SF1 SF3A1 SF3B4 SIRT7 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 UBC YWHAB YWHAQ ZMYND19 ZNF207
Entrez ID		9532	79084
HPRD ID		04859	14387
Ensembl ID		ENSG00000112208	ENSG00000116455
Uniprot IDs		O95816	A0A024R0H7 Q9BQA1
PDB IDs			4GQB 4X60 4X61 4X63 5C9Z 5EMJ 5EMK 5EML 5EMM 5FA5 6CKC 6K1S 6RLL 6RLQ 6UGH 6UXX 6UXY 6V0N 6V0O 6V0P 7BO7 7KIB 7KIC 7KID 7L1G 7M05 7MX7 7MXA 7MXC 7MXG 7MXN 7S0U 7S1P 7S1Q 7S1R 7S1S 7SER 7SES 7U30 7UOH 7UY1 7UYF 7ZUP 7ZUQ 7ZUU 7ZUY 7ZV2 7ZVL 7ZVU 8CSG 8CTB 8CYI 8G1U 8VEO 8VET 8VEU 8VEW 8VEX 8VEY 8X6L 9C10 9DOD 9E3A 9E3B 9EYU 9EYV 9EYW 9EYX 9MGL 9MGM 9MGN 9MGP 9MGQ 9MGR 9N3N 9N3O 9N3P 9N3Q 9N3R
Enriched GO Terms of Interacting Partners?		C3HC4-type RING Finger Domain Binding Cytoplasm Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ATP-dependent Protein Folding Chaperone Nucleotide Binding ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Clathrin Coat Disassembly Positive Regulation Of Wnt Signaling Pathway Regulation Of Synaptic Vesicle Transport ATP Binding Protein Serine Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Stability Protein-containing Complex Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis MRNA Metabolic Process Spliceosomal Complex RNA Splicing Response To Stress Protein Serine/threonine Kinase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Heat Shock Protein Binding MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Oxidative Stress Protein Folding Regulation Of Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing Cellular Response To Stress Negative Regulation Of Autophagosome Assembly Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Response To Unfolded Protein Protein Kinase Activity Adenyl-nucleotide Exchange Factor Activity Mitochondrion Organization Cellular Response To Chemical Stress Regulation Of Cellular Response To Stress Intracellular Signal Transduction Syntaxin-1 Binding Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Ubiquitin Protein Ligase Binding	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex RNA Splicing MRNA Processing MRNA Metabolic Process Methylosome RNA Processing RNA Metabolic Process Spliceosomal Complex Assembly PICln-Sm Protein Complex Catalytic Step 2 Spliceosome U2-type Prespliceosome Assembly Spliceosomal SnRNP Assembly U2 SnRNP Protein-RNA Complex Assembly Nucleic Acid Metabolic Process U2-type Spliceosomal Complex RNA Binding 7-methylguanosine Cap Hypermethylation U2-type Catalytic Step 2 Spliceosome U2-type Precatalytic Spliceosome Nucleoplasm U1 SnRNP Nucleus U4 SnRNP U12-type Spliceosomal Complex Nucleobase-containing Compound Metabolic Process Small Nuclear Ribonucleoprotein Complex SMN-Sm Protein Complex Precatalytic Spliceosome U5 SnRNP U4/U6 X U5 Tri-snRNP Complex Macromolecule Metabolic Process U7 SnRNP Ribonucleoprotein Complex MRNA Binding Macromolecule Methylation Methylation RNA Methylation Commitment Complex Protein-containing Complex Assembly Nucleic Acid Binding Protein-containing Complex Organization RNA Modification CGMP-dependent Protein Kinase Activity MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome Telomerase Holoenzyme Complex Histone Pre-mRNA DCP Binding
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