BAG2 and DNAJC6

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		BAG2	DNAJC6
Gene Name		BCL2-associated athanogene 2	DnaJ (Hsp40) homolog, subfamily C, member 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Synapse
	Molecular Function	Protein Binding Identical Protein Binding Chaperone Binding	Protein Tyrosine Phosphatase Activity SH3 Domain Binding
	Biological Process	Protein Folding Protein Metabolic Process	Post-Golgi Vesicle-mediated Transport Peptidyl-tyrosine Dephosphorylation Membrane Organization Clathrin Coat Disassembly Regulation Of Clathrin-mediated Endocytosis
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS			Anticoagulant levels ( 22216198)
Protein-Protein Interactions		12 interactors: CCAR2 DNAJC6 HSPA1A HSPA4 HSPA8 MAPKAPK2 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83	3 interactors: AP2A2 BAG2 CLTC
Entrez ID		9532	9829
HPRD ID		04859	16326
Ensembl ID			ENSG00000116675
Uniprot IDs		B4DXE2 O95816	O75061
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Heat Regulation Of Cellular Response To Heat Response To Heat MRNA Metabolic Process RNA Splicing Response To Temperature Stimulus MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Clathrin Coat Disassembly Gene Expression Response To Abiotic Stimulus RNA Metabolic Process Response To Unfolded Protein Regulation Of Protein Stability Cellular Response To Stress Protein Refolding Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Apoptotic Signaling Pathway Protein Folding Nucleobase-containing Compound Metabolic Process Response To Stress Positive Regulation Of DNA Damage Checkpoint Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Fibril Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Post-Golgi Vesicle-mediated Transport Mitochondrion Organization Protein Stabilization Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Response To Hypoxia Cellular Heat Acclimation Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Fibril Organization Nitrogen Compound Metabolic Process Peptidyl-serine Phosphorylation Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Protein Import Into Mitochondrial Outer Membrane Positive Regulation Of Cellular Respiration Cellular Protein Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hydrogen Peroxide-induced Neuron Death MRNA 3'-splice Site Recognition Regulation Of Cellular Response To Hypoxia	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Negative Regulation Of Hyaluronan Biosynthetic Process Antigen Processing And Presentation Receptor-mediated Endocytosis Endocytosis Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Defense Response To Virus By Virus Transferrin Transport Intracellular Protein Transport Clathrin-mediated Endocytosis Receptor Internalization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Protein Localization To Plasma Membrane Cellular Protein Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Transport Iron Ion Transport Regulation Of ERBB Signaling Pathway Receptor Metabolic Process Regulation Of Defense Response To Virus Vesicle-mediated Transport Establishment Of Protein Localization Post-Golgi Vesicle-mediated Transport Intracellular Transport Ephrin Receptor Signaling Pathway
Tagcloud ?		abolished ameliorates athanogene balance collapse cytochrome dimer disassociation dj elucidated homodimer link modulating monomer monomerization mpp neurodegeneration neuroprotective overexpressed overexpressing parkinson partners pd phenylpyridinium prevents property pulldown strengthening	advances autosomal bring closer determinants dj exome expectation gba genetics incomplete juvenile landscape lrrk2 modulating monogenic outline parkin parkinsonism pd penetrance penetrant pink1 recessive snca synj1 technologies variants vps35
Tagcloud (Difference) ?		abolished ameliorates athanogene balance collapse cytochrome dimer disassociation elucidated homodimer link monomer monomerization mpp neurodegeneration neuroprotective overexpressed overexpressing parkinson partners phenylpyridinium prevents property pulldown strengthening	advances autosomal bring closer determinants exome expectation gba genetics incomplete juvenile landscape lrrk2 monogenic outline parkin parkinsonism penetrance penetrant pink1 recessive snca synj1 technologies variants vps35
Tagcloud (Intersection) ?		dj modulating pd