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BAG2 and DAPK1
Number of citations of the paper that reports this interaction (PubMedID
29513927
)
77
Data Source:
BioGRID
(affinity chromatography technology, pull down)
BAG2
DAPK1
Description
BAG cochaperone 2
death associated protein kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Microtubule
Axon
Dendrite
Protein Folding Chaperone Complex
Dendritic Microtubule
Nucleus
Cytoplasm
Cytoskeleton
Plasma Membrane
Postsynaptic Density
Actin Cytoskeleton
Organelle
Glutamatergic Synapse
DAPK1-calmodulin Complex
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Transmembrane Transporter Binding
Tau Protein Binding
Protein-folding Chaperone Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calcium/calmodulin-dependent Protein Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
GTP Binding
Kinase Activity
Transferase Activity
Syntaxin-1 Binding
Identical Protein Binding
Protein Serine Kinase Activity
Biological Process
Protein Folding
Positive Regulation Of Protein Processing
Protein Metabolic Process
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis
Protein Stabilization
Positive Regulation Of Proteasomal Protein Catabolic Process
Defense Response To Tumor Cell
Regulation Of Response To Tumor Cell
Regulation Of Translation
Protein Phosphorylation
Apoptotic Process
Signal Transduction
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Autophagy
Positive Regulation Of Autophagy
Negative Regulation Of Translation
Intracellular Signal Transduction
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Protein Autophosphorylation
Cellular Response To Type II Interferon
Cellular Response To Hydroperoxide
Apoptotic Signaling Pathway
Positive Regulation Of Autophagic Cell Death
Regulation Of NMDA Receptor Activity
Pathways
Regulation of HSF1-mediated heat shock response
Caspase activation via Dependence Receptors in the absence of ligand
Drugs
5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Phosphoaminophosphonic Acid-Adenylate Ester
6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE
Fostamatinib
Diseases
Bladder cancer
GWAS
Blood pressure (
24954895
)
Cognitive function (
24684796
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Height (
31562340
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Night sleep phenotypes (
27126917
)
Ovarian cancer (
30557369
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Response to gemcitabine in pancreatic cancer (
22293537
)
Interacting Genes
17 interacting genes:
CCAR2
DAPK1
DISC1
DNAJC6
HSPA1A
HSPA4
HSPA8
LRRK1
LRRK2
MAPKAPK2
MFHAS1
NOTCH3
PINK1
PPIH
SLU7
WDR77
WDR83
109 interacting genes:
ABL1
ABLIM1
AHDC1
APEX2
ARRDC1
ARRDC1-AS1
ATF6
BAG2
BAIAP2
C11orf65
CALM1
CAPRIN1
CBLB
CCDC149
CDC42EP3
CDC42SE1
CMTM4
CNTROB
DENND1C
DTWD1
DUS1L
DUX3
EIF4ENIF1
EPHA1
FADD
FAM107A
FBXL14
FBXW11
FIBP
GASK1B
GTF2F1
HYCC2
IKBKG
JHY
LIMA1
LIMS1
LINC02875
LMF2
LNX1
LOXL2
MAPK1
MAPK3
MCM10
MDM2
MIB1
MRGBP
MTHFD2
MYL12B
NCBP3
NECAB1
NECAP1
NR3C1
ORMDL2
PAK6
PAPSS2
PCP4
PHKG2
PIM1
PIM2
POLR2M
PPP1R14A
PPP2R1A
PPP2R2D
PPP2R5A
PRKAG2
PRR16
PRRC2B
PWP1
RAPGEF3
RASGRP2
RCHY1
RFC5
RHBDD1
RPAP3
RPL41
SARNP
SCEL
SCRN3
SCYL1
SGK2
SH2D2A
SLAIN2
SNRPA
SNURF
SNX9
SPATS2
SPRR2G
SRSF10
STARD3
STUB1
STX1A
TAS2R60
TBC1D22B
TNFRSF1A
TPD52L1
TRADD
TRAPPC2
TTC27
TUBB4B
UNC5A
UNC5B
UNC5C
VGLL4
VN1R1
WWTR1
YWHAB
ZAP70
ZMAT4
ZMYM5
Entrez ID
9532
1612
HPRD ID
04859
02902
Ensembl ID
ENSG00000112208
ENSG00000196730
Uniprot IDs
O95816
B4DHI4
P53355
Q59H88
PDB IDs
1IG1
1JKK
1JKL
1JKS
1JKT
1P4F
1WVW
1WVX
1WVY
1YR5
2W4J
2W4K
2X0G
2XUU
2XZS
2Y0A
2Y4P
2Y4V
2YAK
3DFC
3DGK
3EH9
3EHA
3F5G
3F5U
3GU4
3GU5
3GU6
3GU7
3GU8
3GUB
3ZXT
4B4L
4PF4
4TL0
4TXC
4UV0
4YO4
4YPD
5AUT
5AUU
5AUV
5AUW
5AUX
5AUY
5AUZ
5AV0
5AV1
5AV2
5AV3
5AV4
6AAR
6FHA
6FHB
6GY5
6IN4
6QMO
6QN4
7CCU
7CCV
7CCW
8IE5
8IE6
8IE7
8IE8
8ODZ
8OE0
8OE4
8PB1
9DUB
9DUE
9INV
9INW
9INX
9MIU
Enriched GO Terms of Interacting Partners
?
C3HC4-type RING Finger Domain Binding
Cytoplasm
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
ATP-dependent Protein Folding Chaperone
Nucleotide Binding
ATP-dependent Protein Disaggregase Activity
Vesicle Uncoating
Clathrin Coat Disassembly
Positive Regulation Of Wnt Signaling Pathway
Regulation Of Synaptic Vesicle Transport
ATP Binding
Protein Serine Kinase Activity
Regulation Of Signal Transduction
Regulation Of Protein Stability
Protein-containing Complex Organization
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
MRNA Metabolic Process
Spliceosomal Complex
RNA Splicing
Response To Stress
Protein Serine/threonine Kinase Activity
Regulation Of Intrinsic Apoptotic Signaling Pathway
Heat Shock Protein Binding
MRNA Splicing, Via Spliceosome
Regulation Of Proteasomal Protein Catabolic Process
Cellular Response To Oxidative Stress
Protein Folding
Regulation Of Protein-containing Complex Assembly
RNA Splicing, Via Transesterification Reactions
MRNA Processing
Cellular Response To Stress
Negative Regulation Of Autophagosome Assembly
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Cell Communication
Regulation Of Signaling
Response To Unfolded Protein
Protein Kinase Activity
Adenyl-nucleotide Exchange Factor Activity
Mitochondrion Organization
Cellular Response To Chemical Stress
Regulation Of Cellular Response To Stress
Intracellular Signal Transduction
Syntaxin-1 Binding
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Catabolic Process
Cytosol
Calcium/calmodulin-dependent Protein Kinase Activity
Ubiquitin Protein Ligase Binding
Cytosol
Netrin Receptor Activity
Phosphotyrosine Residue Binding
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Catabolic Process
Positive Regulation Of Proteolysis
Anterior/posterior Axon Guidance
Netrin-activated Signaling Pathway
Positive Regulation Of Cytoskeleton Organization
Bergmann Glial Cell Differentiation
Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA
Astrocyte Differentiation
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Interleukin-34-mediated Signaling Pathway
Regulation Of Protein Stability
Protein Phosphatase Type 2A Complex
Apoptotic Process
Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Regulation Of Golgi Inheritance
Tumor Necrosis Factor Receptor Superfamily Complex
Thymus Development
Programmed Cell Death
Cell Death
Cytoplasm
Positive Regulation Of Organelle Organization
Protein Kinase Activity
Caveolin-mediated Endocytosis
Positive Regulation Of Macrophage Proliferation
ERBB2 Signaling Pathway
Positive Regulation Of Cellular Component Biogenesis
Kinase Binding
Endocytosis
Regulation Of Cytoskeleton Organization
Receptor Serine/threonine Kinase Binding
Protein Domain Specific Binding
Regulation Of Protein Catabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Actin Filament Bundle Assembly
T Cell Receptor Signaling Pathway
Lymphocyte Homeostasis
Cardiac Neural Crest Cell Development Involved In Heart Development
Trachea Formation
Death-inducing Signaling Complex
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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