SYT6

Description		synaptotagmin 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Exocytic Vesicle Perinuclear Endoplasmic Reticulum
	Molecular Function	SNARE Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Protein Homodimerization Activity Metal Ion Binding Calcium Ion Sensor Activity
	Biological Process	Chemical Synaptic Transmission Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Acrosomal Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Breast cancer (prognosis) ( 23319801) Obesity-related traits ( 23251661) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: APP BRCA1 CCDC136 CCDC57 CNTROB DVL3 FXR1 FXR2 GMCL1 GOLGA2 HMBOX1 HOOK2 KANK2 KCTD9 KIF24 KIFC3 KRT40 LMNA LZTS1 MAD1L1 MCC MTUS2 NRXN1 PRKCB TNIP1 TRIM27 TRIM32 TSGA10 ZBTB43 ZBTB8A
Entrez ID		148281
HPRD ID		09654
Ensembl ID		ENSG00000134207
Uniprot IDs		A0A7I2PMW4 I6L9C3 Q5T7P8
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Centrosome Microtubule-based Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Microtubule Organizing Center Organization Nuclear Pore Localization NMDA Selective Glutamate Receptor Signaling Pathway Presynaptic Modulation Of Chemical Synaptic Transmission Microtubule Binding Positive Regulation Of Long-term Neuronal Synaptic Plasticity Cytoskeleton Regulation Of Cell Projection Organization Regulation Of Organelle Organization Regulation Of Neuronal Synaptic Plasticity Modulation Of Chemical Synaptic Transmission Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Component Organization Organelle Assembly Centriole Acetylcholine Receptor Binding Positive Regulation Of Biosynthetic Process Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Microtubule Negative Regulation Of Viral Process Cytoplasm Negative Regulation Of Viral Transcription Cellular Component Assembly Suppression Of Viral Release By Host Regulation Of Synaptic Plasticity Translation Regulator Activity Negative Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Viral Transcription Presynapse Positive Regulation Of RNA Metabolic Process Organelle Organization Regulation Of Cell Projection Assembly Regulation Of Cilium Assembly Protein Binding Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Cilium Assembly Centriole Replication Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Autophagy Positive Regulation Of Gene Expression Regulation Of Presynapse Organization Regulation Of Presynapse Assembly
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