RAB27B and SYTL4

Number of citations of the paper that reports this interaction (PMID 11956164)
25

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro, in vivo)

		RAB27B	SYTL4
Gene Name		RAB27B, member RAS oncogene family	synaptotagmin-like 4
Image
Gene Ontology Annotations	Cellular Component	Golgi Stack Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Endosome Centrosome Plasma Membrane Synaptic Vesicle Extrinsic Component Of Membrane Secretory Granule Transport Vesicle Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Transporter Activity Phospholipid Binding Zinc Ion Binding Rab GTPase Binding Neurexin Family Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Multivesicular Body Sorting Pathway	Intracellular Protein Transport Exocytosis Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	12 interactors: CCDC85B CEP70 FXR2 HMG20A INS RAB27A RAB27B RAB3A RAB8A STX1A STXBP1 ZBTB7B
Entrez ID		5874	94121
HPRD ID		04846	06735
Ensembl ID		ENSG00000041353	ENSG00000102362
Uniprot IDs		O00194	A8K973 B2R7R4 Q71SF7 Q96C24
PDB IDs		2F7S	2CSZ 3FDW
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Secretion Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Positive Regulation Of Secretion Protein Localization Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Transport Transport Positive Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Deoxyhypusine Biosynthetic Process From Spermidine Granuloma Formation Spermidine Catabolic Process Multivesicular Body Sorting Pathway Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Positive Regulation Of Protein Secretion Glucose Homeostasis Natural Killer Cell Degranulation Regulation Of Cellular Localization Chronic Inflammatory Response Positive Regulation Of Mucus Secretion Germinal Center Formation Positive Regulation Of Protein Transport Regulation Of Mucus Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Protein Secretion Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Mast Cell Degranulation Regulation Of Cell Activation Polyamine Metabolic Process Leukocyte Mediated Cytotoxicity Regulation Of Mast Cell Activation Melanocyte Differentiation Negative Regulation Of Insulin Secretion Regulation Of Regulated Secretory Pathway Melanosome Localization Leukocyte Degranulation Negative Regulation Of Peptide Secretion	Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Regulation Of Exocytosis Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Establishment Of Organelle Localization Positive Regulation Of Secretion Exocytosis Regulation Of Secretion Regulation Of Vesicle-mediated Transport Rab Protein Signal Transduction Organelle Localization Secretion By Cell Regulation Of Cellular Localization Neurotransmitter Secretion Glutamate Secretion Secretion Protein Secretion Regulation Of Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Transport Regulation Of Synaptic Vesicle Transport Neurotransmitter Transport Multivesicular Body Sorting Pathway Cell-cell Signaling Synaptic Vesicle Exocytosis Vesicle Organization Acid Secretion Ras Protein Signal Transduction Regulation Of Neurotransmitter Secretion Synaptic Transmission Regulation Of Synaptic Vesicle Priming Dicarboxylic Acid Transport Regulation Of Synaptic Transmission Synaptic Vesicle Maturation Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Energy Reserve Metabolic Process Positive Regulation Of Regulated Secretory Pathway Intracellular Protein Transport Neuromuscular Synaptic Transmission Amino Acid Transport Regulation Of Synaptic Plasticity Melanosome Transport
Tagcloud ?		7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg	acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e plscr4 profoundly saponin slc27a3 triglycerides vldlr
Tagcloud (Difference) ?		7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg	acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e plscr4 profoundly saponin slc27a3 triglycerides vldlr
Tagcloud (Intersection) ?