CD28 and ITK

  • Number of citations of the paper that reports this interaction (PMID 15144186)
  • 48
  • Data Source:
  • HPRD (in vivo, in vitro)

CD28

ITK

Gene Name CD28 molecule IL2-inducible T-cell kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 17 interactors: CD247 CD4 CD80 CD86 DUSP14 GRAP2 GRB2 IL12A ITK LCK LRRC23 NSF PIK3CG PIK3R1 PIK3R2 PLCG1 PTPRC 29 interactors: BLNK BMX BTK CBL CD28 DOK1 ERBB2 ERBB3 FASLG FGFR1 FYN GRB2 HNRNPK IKBKG KHDRBS1 KPNA2 LAT LCK LCP2 PLCG1 PLCG2 PPIA SH2D2A SMAD4 SOCS1 SPRR2A SRC TGFBR1 WAS
Entrez ID 940 3702
HPRD ID 01727 01746
Ensembl ID ENSG00000178562 ENSG00000113263
Uniprot IDs B4E0L1 P10747 Q08881
PDB IDs 1YJD 1SM2 1SNU 1SNX 2E6I 2LMJ 2YUQ 3MIY 3MJ1 3MJ2 3QGW 3QGY 3T9T 3V5J 3V5L 3V8T 3V8W 4HCT 4HCU 4HCV 4KIO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerated  allows  augment  b7  catalytically  cd28re  composite  concert  consistently  converge  costimulatory  element  herein  ikappab  ikk  ikkalpha  ikkbeta  ikks  inactive  initiated  interleukin  liberated  mitogen  presenting  proteasome  robust  tcr  transactivation  upstream 
adrenergic  ark  bind  btk  coincides  computer  databases  defects  difficult  difficulty  domains  find  homologues  homology  hypothesis  irs  overcome  ph  pleckstrin  program  programs  simple  substrate  teca  termini  transduction  trimeric  unrecognized  widely 
Tagcloud (Difference) ?
accelerated  allows  augment  b7  catalytically  cd28re  composite  concert  consistently  converge  costimulatory  element  herein  ikappab  ikk  ikkalpha  ikkbeta  ikks  inactive  initiated  interleukin  liberated  mitogen  presenting  proteasome  robust  tcr  transactivation  upstream 
adrenergic  ark  bind  btk  coincides  computer  databases  defects  difficult  difficulty  domains  find  homologues  homology  hypothesis  irs  overcome  ph  pleckstrin  program  programs  simple  substrate  teca  termini  transduction  trimeric  unrecognized  widely 
Tagcloud (Intersection) ?