TAOK2 and TUBA1A

Number of citations of the paper that reports this interaction (PMID 12639963)
16

Data Source:
BioGRID (pull down)

		TAOK2	TUBA1A
Gene Name		TAO kinase 2	tubulin, alpha 1a
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytoskeleton Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Dendrite Cytoplasmic Vesicle Membrane Receptor Complex	Nucleus Cytosol Microtubule Cytoplasmic Microtubule Cytoplasmic Ribonucleoprotein Granule Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding Mitogen-activated Protein Kinase Kinase Binding	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding
	Biological Process	Activation Of MAPKK Activity Regulation Of Cell Growth Protein Phosphorylation Protein Targeting To Membrane Apoptotic Process Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization G2 DNA Damage Checkpoint Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of JNK Cascade Focal Adhesion Assembly Stress-activated MAPK Cascade	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Folding Organelle Organization Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Cell Division
Pathways			Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane L1CAM interactions G2/M Transition Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Regulation of PLK1 Activity at G2/M Transition Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Loss of Nlp from mitotic centrosomes Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs			Albendazole Vinblastine Mebendazole Epothilone D Epothilone B 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ELK1 KLHL12 MAP2K3 MAP2K6 MEGF10 RCHY1 TUBA1A TUBA4A TUBB	53 interactors: ANXA7 ARL3 ATXN3 B4GALT1 BTG1 C8orf33 CDKN1A CDKN2A CLIP1 CNP CXCR1 CYLD DAG1 DUSP23 EGFR GEMIN7 GRM7 GSK3B GZMB HTRA2 KEL KPNB1 LRRK2 MAP2 MAPK6 MAPRE1 MAX MYC NFATC1 NUDT3 PAFAH1B1 PFDN1 PLA2G7 SDC3 SIAH1 SMN1 SNCA SOCS6 SOCS7 SPG20 STARD13 SYK TAOK2 TIMM17A TK1 TLN1 TTR TUBB UBE2D3 VAV1 VCL YWHAQ ZAP70
Entrez ID		9344	7846
HPRD ID		18147	03959
Ensembl ID		ENSG00000149930	ENSG00000167552
Uniprot IDs		Q9UL54	Q71U36
PDB IDs
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Protein Polymerization Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response MAPK Cascade Regulation Of Innate Immune Response Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To Interleukin-4 Signal Transduction By Phosphorylation Innate Immune Response Response To Interleukin-4 Cardiac Muscle Contraction 'de Novo' Posttranslational Protein Folding Cellular Protein Complex Assembly 'de Novo' Protein Folding Heart Contraction Protein Complex Assembly Cell Cycle Process Skeletal Muscle Satellite Cell Proliferation Striated Muscle Contraction Microtubule Cytoskeleton Organization Immune Response-regulating Signaling Pathway Cellular Response To Testosterone Stimulus Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Activation Immune Response Defense Response Cell Cycle Cellular Response To Sorbitol Cytoskeleton-dependent Intracellular Transport Activation Of MAPK Activity Cellular Macromolecular Complex Assembly Positive Regulation Of Immune Response	Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cell Communication Cell Death Death Intracellular Signal Transduction Signaling Programmed Cell Death Response To Stimulus Response To Organic Substance Positive Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Response To Stress Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Apoptotic Process Developmental Process Cell Cycle Regulation Of Intracellular Transport System Development Regulation Of Intracellular Signal Transduction Defense Response Regulation Of Signal Transduction Regulation Of Signaling Cellular Response To Organic Substance Cellular Process Negative Regulation Of Intracellular Signal Transduction Locomotion Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Immune System Process Anatomical Structure Development Signal Transduction Regulation Of Phosphorylation Regulation Of Cell Death Immune Response-regulating Signaling Pathway Neuron Development Regulation Of Growth Nervous System Development Cell Differentiation Cell Development Regulation Of Kinase Activity Neuron Projection Morphogenesis Regulation Of Cellular Process Multicellular Organismal Development Innate Immune Response Cell Projection Morphogenesis Cell Migration
Tagcloud ?			brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread
Tagcloud (Difference) ?			brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread
Tagcloud (Intersection) ?