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UBE2Q2 and BIRC2
Number of citations of the paper that reports this interaction (PMID
21113135
)
52
Data Source:
BioGRID
(two hybrid)
UBE2Q2
BIRC2
Gene Name
ubiquitin-conjugating enzyme E2Q family member 2
baculoviral IAP repeat containing 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
XY Body
Nucleus
Cytoplasm
Cytosol
Spindle Microtubule
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Membrane Raft
Molecular Function
Ubiquitin-protein Transferase Activity
ATP Binding
Ligase Activity
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Protein N-terminus Binding
Biological Process
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Response To Hypoxia
Placenta Development
Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cell Surface Receptor Signaling Pathway
Regulation Of Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Regulation Of RIG-I Signaling Pathway
Regulation Of Cell Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Regulation Of Innate Immune Response
Response To Ethanol
Regulation Of Cell Differentiation
Regulation Of Inflammatory Response
Protein Heterooligomerization
Response To CAMP
Regulation Of Cell Cycle
Regulation Of Necroptotic Process
Negative Regulation Of Necroptotic Process
Necroptotic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Mitotic Spindle Assembly
Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Apoptotic cleavage of cellular proteins
IKK complex recruitment mediated by RIP1
TRIF-mediated TLR3/TLR4 signaling
Apoptotic execution phase
MyD88-independent cascade
Activated TLR4 signalling
Toll-Like Receptors Cascades
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
NOD1/2 Signaling Pathway
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Programmed Cell Death
Innate Immune System
Drugs
Diseases
GWAS
Chronic kidney disease (
20383146
)
Urate levels (
23263486
)
Prostate cancer (
23535732
)
Protein-Protein Interactions
4 interactors:
BIRC2
BIRC3
PCGF2
RNF111
58 interactors:
BIRC5
BIRC7
BOLA1
CASP2
CASP3
CASP7
CASP9
CBLC
CD40
DIABLO
DZIP3
EAF2
EXOSC5
FBXO7
GAS1
GCC1
GFAP
GSPT1
HSP90B1
HTRA2
IKBKE
IKBKG
JUP
LTBR
MAGEA11
MAP3K2
MAP3K3
NMB
OTUB1
PACS2
PCSK9
PPM1K
RAC1
RAF1
RHOA
RIPK1
RIPK2
RIPK3
RIPK4
RNF181
TRADD
TRAF1
TRAF2
TRIM34
TSG101
TSGA10
UBB
UBC
UBE2B
UBE2D1
UBE2D2
UBE2D3
UBE2J1
UBE2Q2
UBE2S
UBE2V1
UBE2W
WDYHV1
Entrez ID
92912
329
HPRD ID
14294
03419
Ensembl ID
ENSG00000140367
ENSG00000110330
Uniprot IDs
C9JX13
Q8WVN8
Q13490
PDB IDs
1ZUO
1QBH
2L9M
3D9T
3D9U
3M1D
3MUP
3OZ1
3T6P
3UW4
4EB9
4HY4
4HY5
4LGE
4LGU
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Protein Ubiquitination
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Negative Regulation Of Necroptotic Process
Negative Regulation Of Necrotic Cell Death
Regulation Of RIG-I Signaling Pathway
Regulation Of Necroptotic Process
Regulation Of Protein Ubiquitination
Regulation Of Necrotic Cell Death
Necroptotic Process
Regulation Of Toll-like Receptor Signaling Pathway
NIK/NF-kappaB Signaling
Programmed Necrotic Cell Death
Necrotic Cell Death
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Regulation Of Defense Response To Virus
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Toll-like Receptor Signaling Pathway
Positive Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Protein Monoubiquitination
Positive Regulation Of Protein K48-linked Ubiquitination
Protein Heterooligomerization
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Regulation Of Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Protein Modification Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of Cell Death
Regulation Of Signaling
Protein Polyubiquitination
Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Innate Immune Response
Cellular Protein Modification Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Protein Metabolic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Regulation Of Protein Monoubiquitination
Programmed Cell Death
Cell Death
Death
Apoptotic Process
Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Activation Of Innate Immune Response
Regulation Of Protein Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Apoptotic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of Innate Immune Response
Protein Ubiquitination
Cellular Response To Stress
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cellular Protein Metabolic Process
Protein Polyubiquitination
Protein Processing
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Innate Immune Response
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Signal Transduction
Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cell Death
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Transferase Activity
Response To Stress
Cellular Protein Catabolic Process
Cellular Protein Modification Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Cellular Protein Metabolic Process
Tagcloud
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Difference)
?
2b
arrest
baculoviral
c4
caspases
cdk2
ciap1
consumer
deacetylases
dependently
du
ester
hdacs
immortalized
lncap
maa
malformation
methoxyacetic
named
p63
p73
pharmaceutical
phthalates
prns
prostatic
rwpe
spermatocyte
suppresses
turning
Tagcloud (Intersection)
?