TIFA and SDCBP2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		TIFA	SDCBP2
Gene Name		TRAF-interacting protein with forkhead-associated domain	syndecan binding protein (syntenin) 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein C-terminus Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling	Nervous System Development Intracellular Signal Transduction Intracellular Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: AP1M1 ARHGEF39 DVL2 IRAK1 LNX1 NIF3L1 NUDT18 NXF1 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF2 TRAF6 TXN2	41 interactors: ADAP1 ARF4 BEND7 C11orf57 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR NFASC NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		92610	27111
HPRD ID		09835	18032
Ensembl ID			ENSG00000125775
Uniprot IDs		Q96CG3	Q9H190
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of JUN Kinase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Immunoglobulin Secretion Regulation Of MAPK Cascade Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-1-mediated Signaling Pathway Positive Regulation Of T Cell Cytokine Production Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Interleukin-2 Production Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Autoubiquitination Positive Regulation Of Transferase Activity Protein Ubiquitination Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokine Production Involved In Immune Response Protein Modification By Small Protein Conjugation Regulation Of Innate Immune Response Response To External Stimulus Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Cellular Component Assembly Protein Complex Assembly Involved In Synapse Maturation Fertilization, Exchange Of Chromosomal Proteins Gamma-aminobutyric Acid Receptor Clustering Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Cellular Nitrogen Compound Metabolic Process Locomotion MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Assembly Male Pronucleus Assembly Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Protein-pyridoxal-5-phosphate Linkage Transsulfuration Tryptophan Catabolic Process To Acetyl-CoA Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Gephyrin Clustering Synaptic Vesicle Clustering Hydrogen Sulfide Biosynthetic Process
Tagcloud ?		activate activates catalyzing conjugating consisting crude cytosolic defective exists forkhead ikk interesting ligase lys oligomeric oligomerization oligomers polyubiquitin polyubiquitination really reconstitution t2bp tak1 traf traf6 transforming ub ubc13 uev1a
Tagcloud (Difference) ?		activate activates catalyzing conjugating consisting crude cytosolic defective exists forkhead ikk interesting ligase lys oligomeric oligomerization oligomers polyubiquitin polyubiquitination really reconstitution t2bp tak1 traf traf6 transforming ub ubc13 uev1a
Tagcloud (Intersection) ?