SDCBP2 and ARF4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SDCBP2	ARF4
Description		syndecan binding protein 2	ARF GTPase 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Nucleotide Binding GTPase Activity Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding NAD+-protein-arginine ADP-ribosyltransferase Activity Phospholipase D Activator Activity
	Biological Process	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Epidermal Growth Factor Receptor Signaling Pathway Learning Protein Transport Vesicle-mediated Transport Cell Migration Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Regulation Of Synapse Organization Cilium Assembly Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Cilium Assembly Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2	16 interacting genes: ADRB2 APBA1 APBA2 APBA3 COPS3 DENND1A DENND1B EGFR HNRNPD IKBKG PTEN RAB11FIP3 RCHY1 SDCBP2 SIRPA SUMO2
Entrez ID		27111	378
HPRD ID		18032	03107
Ensembl ID		ENSG00000125775	ENSG00000168374
Uniprot IDs		Q9H190	P18085
PDB IDs			1Z6X
Enriched GO Terms of Interacting Partners?		Protein Binding	Dendritic Spine Amyloid-beta Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Size Positive Regulation Of Proteolysis Regulation Of Protein Metabolic Process Endocytic Recycling Regulation Of Macromolecule Metabolic Process In Utero Embryonic Development Chordate Embryonic Development Regulation Of Cell Communication Regulation Of Signaling Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Establishment Of Protein Localization Regulation Of Metabolic Process Chemical Synaptic Transmission Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Trans-synaptic Signaling Synaptic Signaling Regulation Of Protein Modification Process Vesicle-mediated Transport To The Plasma Membrane Phosphatidylinositol Phosphate Binding Cerebral Cortex Cell Migration Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Cellular Localization Regulation Of Gene Expression Protein Transport Regulation Of Proteolysis Establishment Of Localization In Cell Protein Homodimerization Activity Cellular Response To Estradiol Stimulus Enzyme Binding Regulation Of Macromolecule Biosynthetic Process Response To Electrical Stimulus Positive Regulation Of Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Mini Excitatory Postsynaptic Potential Intracellular Transport Presynaptic Modulation Of Chemical Synaptic Transmission Locomotory Behavior
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